Activating Compound | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | activation | Onchocerca volvulus | |
catalase | activation | Onchocerca volvulus | |
dithiothreitol | activation | Onchocerca volvulus |
Cloned (Comment) | Organism |
---|---|
identification of three cDNAs encoding putative alpha subunits of the enzyme, co-expression of one of these with protein-disulfide isomerase in a catalytically active form in an insect system, genomic structure | Onchocerca volvulus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Brugia malayi | |
Coumalic acid | - |
Brugia malayi | |
daunorubicin | - |
Brugia malayi | |
doxorubicin | - |
Brugia malayi | |
Pyridine 2,4-dicarboxylate | not inhibitory | Brugia malayi |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | - |
Onchocerca volvulus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Brugia malayi | - |
- |
- |
Onchocerca volvulus | Q95W51 | - |
- |
Onchocerca volvulus | Q95W53 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protocollagen + 2-oxoglutarate + O2 | - |
Onchocerca volvulus | 4-hydroxyproline containing protocollagen + succinate + CO2 | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Onchocerca volvulus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
2-oxoglutarate | - |
Onchocerca volvulus | |
ascorbate | - |
Onchocerca volvulus |