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Literature summary for 1.14.11.17 extracted from
- Facile synthesis of 1,1-[2H2]-2-methylaminoethane-1-sulfonic acid as a substrate for taurine a ketoglutarate dioxygenase (TauD) (2009), Tetrahedron Lett., 50, 611-613.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | model system for non-heme iron oxygenases | Escherichia coli |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0051 | - |
N-methyltaurine | deuterated substrate | Escherichia coli |  |
| 0.0056 | - |
O2 | deuterated substrate 2-methyltaurine | Escherichia coli | |
| 0.0194 | - |
taurine | - |
Escherichia coli | |
| 0.041 | - |
O2 | commercially available substrate 2-methyltaurine | Escherichia coli | |
| 0.041 | - |
O2 | substrate taurine | Escherichia coli | |
| 0.046 | - |
O2 | substrate 2-methyltaurine | Escherichia coli | |
| 0.048 | - |
N-methyltaurine | commercially available substrate | Escherichia coli | |
| 0.054 | - |
N-methyltaurine | - |
Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-methyltaurine + 2-oxoglutarate + O2 | - |
Escherichia coli | CO2 + succinate + sulfite + methylaminoacetaldehyde | - |
? | |
| taurine + 2-oxoglutarate + O2 | - |
Escherichia coli | CO2 + succinate + sulfite + aminoacetaldehyde | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TauD | - |
Escherichia coli |
| taurine alpha ketoglutarate dioxygenase | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | important in antibiotic biosynthesis, oxygen sensing, DNA repair, biodegradation of anthropogenic compounds | Escherichia coli |
kcat/KM [mM/s]
| kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00000001 | - |
O2 | substrate 2-methyltaurine | Escherichia coli | |
| 0.000000011 | - |
O2 | deuterated substrate 2-methyltaurine | Escherichia coli | |
| 0.000000012 | - |
O2 | commercially available substrate 2-methyltaurine | Escherichia coli | |
| 0.000000012 | - |
O2 | sustrate taurine | Escherichia coli | |
| 0.000000025 | - |
taurine | - |
Escherichia coli | |
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Release 2023.1 (January 2023)
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