Literature summary for 1.14.11.17 extracted from

Elkins, J.M.; Ryle, M.J.; Clifton, I.J.; Dunning Hotopp, J.C.; Lloyd, J.S.; Burzlaff, N.I.; Baldwin, J.E.; Hausinger, R.P.; Roach, P.L.
X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates (2002), Biochemistry, 41, 5185-5192.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop method, inclusion of taurine and 2-oxoglutarate is absolutely required for crystal formation	Escherichia coli

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Fe2+	required, essential cofactor	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
taurine + 2-oxoglutarate + O2	Escherichia coli	enables the use of taurine as sulfur source	sulfite + aminoacetaldehyde + succinate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P37610	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
additional information	Trp128, Trp240, and Trp248 are hydroxylated upon exposure to oxygen	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
taurine + 2-oxoglutarate + O2	-	Escherichia coli	sulfite + aminoacetaldehyde + succinate + CO2	-	?
taurine + 2-oxoglutarate + O2	enables the use of taurine as sulfur source	Escherichia coli	sulfite + aminoacetaldehyde + succinate + CO2	-	?

Subunits

Subunits	Comment	Organism
dimer	crystal structure analysis	Escherichia coli

Synonyms

Synonyms	Comment	Organism
TauD	-	Escherichia coli
taurine/alpha-ketoglutarate dioxygenase	-	Escherichia coli

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Release 2023.1 (January 2023)