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Literature summary for 1.14.11.16 extracted from

  • Lyu, F.; Xue, Q.; Gao, S.
    Research progress of aspartyl-(asparaginyl) beta-hydroxylase in tumors (2015), Cancer Res. Clinic, 27, 280-282 .
No PubMed abstract available
Search for more literature for 1.14.11.16

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane type 2 transmembrane protein. The enzyme can translocate to cell membrane from the endoplasmic reticulum membrane when it is overexpressed in cancer cell, which hydroxylate proteins such as Notch, Jagged, and cellular adhesion molecules that regulate cell migration and invasion Homo sapiens 16020
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q12797
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Source Tissue

Source Tissue Comment Organism Textmining
paranephros
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 Homo sapiens
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placenta
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
AAH
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens overexpression in many types of cancer tissues up

General Information

General Information Comment Organism
drug target the enzyme is a potential biomarker for cancer diagnosis Homo sapiens
metabolism the enzyme catalyzes the hydroxylation of specific aspartyl and asparaginyl residues in epidermal growth factor-like domains of proteins Homo sapiens