Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3',5'-cyclic AMP | - |
Photinus pyralis | |
ATP | uncomplexed ATP is a competitive inhibitor with respect to MgATP2- complex | Photinus pyralis | |
dAMP | - |
Photinus pyralis | |
dATP | - |
Photinus pyralis | |
MgATP2- | - |
Photinus pyralis | |
phosphate | - |
Photinus pyralis | |
ribose-5-phosphate | - |
Photinus pyralis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.025 | - |
MgATP2- | - |
Photinus pyralis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | - |
Photinus pyralis | |
Mg2+ | necessary for the activation step | Photinus pyralis | |
Mn2+ | influences the interaction with triazine dyes | Photinus pyralis | |
additional information | Ba2+ inactivates and Hg2+ is inhibitor | Photinus pyralis | |
additional information | activity in decreasing order: Mn2+, Mg2+, Co2+/Zn2+/Fe2+, Cd2+, Ni2+, Ca2+, Sr2+ | Photinus pyralis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Photinus pyralis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxyATP + Photinus luciferin | - |
Photinus pyralis | oxidized Photinus luciferin + CO2 + H2O + AMP + diphosphate + hv | - |
? | |
luciferin + MgATP2- | - |
Photinus pyralis | AMP + diphosphate | - |
? | |
Photinus luciferin + O2 + ATP | the true substrate is MgATP2- | Photinus pyralis | oxidized Photinus luciferin + CO2 + H2O + AMP + diphosphate + hv | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | two non identical subunits | Photinus pyralis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.3 | - |
phosphate | - |
Photinus pyralis | |
0.34 | - |
ribose-5-phosphate | - |
Photinus pyralis | |
0.7 | - |
dATP | - |
Photinus pyralis | |
0.9 | - |
dAMP | - |
Photinus pyralis | |
0.9 | - |
3',5'-cyclic AMP | - |
Photinus pyralis | |
1 | - |
MgATP2- | - |
Photinus pyralis |