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Literature summary for 1.13.12.16 extracted from

  • Francis, K.; Gadda, G.
    Kinetic evidence for an anion binding pocket in the active site of nitronate monooxygenase (2009), Bioorg. Chem., 37, 167-172.
    View publication on PubMed
Search for more literature for 1.13.12.16

Inhibitors

Inhibitors Comment Organism Structure
Butanal competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
hexanal competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
KBr competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
KBr
-
 Neurospora crassa
KCl competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
KCl
-
 Neurospora crassa
KF competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
KF
-
 Neurospora crassa
KI competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
KI
-
 Neurospora crassa
NaNO2 competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
NaNO2 competitive inhibitor with respect to ethylnitronate as substrate Neurospora crassa
NaNO3 competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
NaNO3
-
 Neurospora crassa
pentanal competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii
propanal competitive inhibitor with respect to ethylnitronate as substrate Cyberlindnera mrakii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetic parameters of reductive half reaction Cyberlindnera mrakii

Organism

Organism UniProt Comment Textmining
Cyberlindnera mrakii
-
-
-
Neurospora crassa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 butyl-1-nitronate + O2
-
 Cyberlindnera mrakii 2 butanal + 2 nitrite
-
 ?
2 ethylnitronate + O2
-
 Cyberlindnera mrakii 2 ethanal + 2 nitrite
-
 ?
2 propyl-1-nitronate + O2
-
 Cyberlindnera mrakii 2 propanal + 2 nitrite
-
 ?
ethyl nitronate + O2
-
 Neurospora crassa ethanal + nitrite
-
 ?
additional information kinetic evidence for an anion binding pocket in the active site of nitronate monooxygenase Neurospora crassa ?
-
 ?
additional information kinetic evidence for an anion binding pocket in the active site of nitronate monooxygenase Cyberlindnera mrakii ?
-
 ?

Synonyms

Synonyms Comment Organism
nitronate monooxygenase
-
 Neurospora crassa
nitronate monooxygenase
-
 Cyberlindnera mrakii

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information kinetic parameters of reductive half reaction Cyberlindnera mrakii

Cofactor

Cofactor Comment Organism Structure
FMN binding of sodium nitrite to the enzyme enzymes induces spectral changes in the FMN cofactor bound at the active site of the enzyme Neurospora crassa
FMN binding of sodium nitrite to the enzyme enzymes induces spectral changes in the FMN cofactor bound at the active site of the enzyme Cyberlindnera mrakii

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.95
-
 KI pH 7.4, 30°C Neurospora crassa
1.7
-
 NaNO3 pH 7.4, 30°C Neurospora crassa
1.9
-
 NaNO3 pH 7.4, 30°C Neurospora crassa
4
-
 KBr pH 7.4, 30°C Neurospora crassa
6
-
 KI pH 7.4, 30°C Cyberlindnera mrakii
9.8
-
 NaNO2 pH 7.4, 30°C Cyberlindnera mrakii
11.3
-
 KCl pH 7.4, 30°C Neurospora crassa
12
-
 NaNO3 pH 7.4, 30°C Cyberlindnera mrakii
20
-
 KBr pH 7.4, 30°C Cyberlindnera mrakii
30
-
 KCl pH 7.4, 30°C Cyberlindnera mrakii
58
-
 propanal pH 7.4, 30°C Cyberlindnera mrakii
58
-
 pentanal pH 7.4, 30°C Cyberlindnera mrakii
60
-
 Butanal pH 7.4, 30°C Cyberlindnera mrakii
60
-
 hexanal pH 7.4, 30°C Cyberlindnera mrakii
77
-
 KF pH 7.4, 30°C Neurospora crassa
125
-
 KF pH 7.4, 30°C Cyberlindnera mrakii