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Literature summary for 1.13.11.71 extracted from

  • Raghuvanshi, S.; Reed, V.; Blaner, W.S.; Harrison, E.H.
    Cellular localization of ?-carotene 15,15 oxygenase-1 (BCO1) and beta-carotene 9,10 oxygenase-2 (BCO2) in rat liver and intestine (2015), Arch. Biochem. Biophys., 572, 19-27 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.13.11.71

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
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additional information subcellular expression and localization of BCO1 and BCO2 proteins in rat liver and intestine, overview Rattus norvegicus
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-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
all-trans-beta-carotene + O2 Rattus norvegicus
-
 all-trans-10'-apo-beta-carotenal + beta-ionone
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus A3KN98
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestine
-
 Rattus norvegicus
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liver BCO2 is highly expressed in hepatocytes and mucosal epithelium Rattus norvegicus
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McArdle-RH7777 cell
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 Rattus norvegicus
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additional information cellular expression and localization of BCO1 and BCO2 proteins in rat liver and intestine, immunohistochemic analysis, overview. BCO2 shows diffuse presence along epithelia with strong immunoreactivity in endothelial cells and in certain epithelial cells, possible intestinal retinoid storage cells Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
all-trans-beta-carotene + O2
-
 Rattus norvegicus all-trans-10'-apo-beta-carotenal + beta-ionone
-
 ?

Synonyms

Synonyms Comment Organism
BCO2
-
 Rattus norvegicus

General Information

General Information Comment Organism
physiological function BCO2 catalyzes eccentric cleavage of both provitamin and non-provitamin A carotenoids which results in the formation of apo-carotenoids such as beta-apo-10' carotenal and beta-ionone Rattus norvegicus