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Literature summary for 1.13.11.68 extracted from

  • Bruno, M.; Koschmieder, J.; Wuest, F.; Schaub, P.; Fehling-Kaschek, M.; Timmer, J.; Beyer, P.; Al-Babili, S.
    Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites (2016), J. Exp. Bot., 67, 5993-6005 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q7XJM2
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Source Tissue

Source Tissue Comment Organism Textmining
seedling
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Arabidopsis thaliana
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(7E,7'E,9Z,9'E)-7',8'-dihydro-psi,psi-carotene + O2
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Arabidopsis thaliana zeta-apo-10'-carotenal + beta-ionone
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?
(7E,7'E,9Z,9'E)-lycopene + O2
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Arabidopsis thaliana zeta-apo-10'-carotenal + beta-ionone
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?
9'-cis-neurosporene + O2 low activity Arabidopsis thaliana zeta-apo-10'-carotenal + beta-ionone
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?
9-cis-zeta-carotene + O2
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Arabidopsis thaliana 9-cis-zeta-apo-10'-carotenal + beta-ionone
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?
additional information enzyme substrate specificity, dynamic modeling, overview. No activity with the tri-cis-configured PDS or ZDS intermediates and products, i.e. 9,15-di-cis-phytofluene, 9,15,9'-tri-cis-zeta-carotene, 7,9,9'-tri-cis-neurosporene, and 7,9,9',7-tetra-cis-lycopene, as well as with non-canonical isomers of phytofluene (9-cis, 15-cis, all-trans). 9-cis-Lycopene is a poor substrate, and all-trans-lycopene is no substrate. AtCCD7 shows specificity for cleavage of the trans-configured C9-C10 double bond Arabidopsis thaliana ?
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?

Synonyms

Synonyms Comment Organism
AtCCD7
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Arabidopsis thaliana
SL biosynthetic enzyme
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Arabidopsis thaliana
strigolactone biosynthetic enzyme
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function CCD7 enzymes are highly stereospecific, cleaving only 9-cis-configured substrates, such as 9-cis-beta-carotene. The strigolactone biosynthetic enzyme AtCCD7 converts 9-cis-configured acyclic carotenes, such as 9-cis-zeta-carotene, 9'-cis-neurosporene, and 9-cis-lycopene, yielding 9-cis-configured products and indicating that AtCCD7, rather than AtCCD4, is the candidate for forming acyclic retrograde signals that are thought to derive from the cleavage of poly-cis-configured carotene desaturation intermediates Arabidopsis thaliana