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Literature summary for 1.13.11.6 extracted from

  • Chiarugi, A.; Moroni, F.
    Effects of mitochondria and o-methoxybenzoylalanine on 3-hydroxyanthranilic acid dioxygenase activity and quinolinic acid synthesis (1999), J. Neurochem., 72, 1125-1132.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
o-methoxybenzoylalanine in whole-liver homogenates, but in purified enzyme preparations only in the presence of mitochondria Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Mus musculus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
liver Mus musculus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [Āµmol/min/mg] Specific Activity Maximum [Āµmol/min/mg] Comment Organism
6.8
-
-
Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxyanthranilate + O2
-
Mus musculus 2-amino-3-carboxymuconate semialdehyde reacts spontaneously to quinolinic acid ?

Subunits

Subunits Comment Organism
monomer 1 * 33000 Mus musculus