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Literature summary for 1.13.11.6 extracted from

  • Malherbe, P.; Koehler, C.; Da Prada, M.; Lang, G.; Kiefer, V.; Schwarcz, R.; Lahm, H.W.; Cesura, A.M.
    Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase (1994), J. Biol. Chem., 269, 13792-13797.
    View publication on PubMed
Search for more literature for 1.13.11.6

Application

Application Comment Organism
medicine plays a role in disorders, associated with altered tissue levels of quinolinic acid Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
expression in human embryonic kidney HEK-293 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32600
-
 immunoblot analysis, recombinant enzyme Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxyanthranilate + O2
-
 Rattus norvegicus 2-amino-3-carboxymuconate semialdehyde reacts spontaneously to quinolinic acid ?