BRENDA - Enzyme Database show
show all sequences of 1.13.11.58

On the substrate binding of linoleate 9-lipoxygenases

Andreou, A.Z.; Hornung, E.; Kunze, S.; Rosahl, S.; Feussner, I.; Lipids 44, 207-215 (2008)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
overexpression in Escherichia coli
Arabidopsis thaliana
overexpression in Escherichia coli
Solanum tuberosum
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Solanum tuberosum
P37831
-
-
Arabidopsis thaliana
Q06327
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-linolenate
-
705465
Solanum tuberosum
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate is the main product
-
-
?
alpha-linolenate + O2
-
705465
Arabidopsis thaliana
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
12-, 13-, and 16-hydroperoxy-(10E,12Z,15Z)-octadecatrienoates are minor byproducts
-
-
?
gamma-linolenate + O2
-
705465
Solanum tuberosum
(6Z,9S,10E,12Z)-9-hydroperoxy-6,10,12-octadecatrienoate
72% (6Z,9S,10E,12Z)-9-hydroperoxy-10,12,15-octadecatrienoate, with racemic 6-, 10-, and 13-gamma-hydroperoxy-(10E,12Z,15Z)-octadecatrienoates as secondary products
-
-
?
linoleate + O2
-
705465
Solanum tuberosum
(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
98% (10E,12Z)-9-hydroperoxy-10,12-octadecadienoate, almost exclusively S stereoconfiguration. (9Z,11E,13S)-13-hydroperoxy-9,11-octadecadienoate is a minor byproduct
-
-
?
linoleate + O2
-
705465
Arabidopsis thaliana
(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
the main product (94%) is (10E,12Z)-9-hydroperoxy-10,12-octadecadienoate, primarily S configuration
-
-
?
additional information
low activity with arachidonate, the C20 fatty acid is converted into a mixture of racemic products
705465
Arabidopsis thaliana
?
-
-
-
-
additional information
low activity with arachidonate, the C20 fatty acid is converted into a mixture of racemic products
705465
Solanum tuberosum
?
-
-
-
-
Cloned(Commentary) (protein specific)
Commentary
Organism
overexpression in Escherichia coli
Arabidopsis thaliana
overexpression in Escherichia coli
Solanum tuberosum
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-linolenate
-
705465
Solanum tuberosum
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate is the main product
-
-
?
alpha-linolenate + O2
-
705465
Arabidopsis thaliana
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate
12-, 13-, and 16-hydroperoxy-(10E,12Z,15Z)-octadecatrienoates are minor byproducts
-
-
?
gamma-linolenate + O2
-
705465
Solanum tuberosum
(6Z,9S,10E,12Z)-9-hydroperoxy-6,10,12-octadecatrienoate
72% (6Z,9S,10E,12Z)-9-hydroperoxy-10,12,15-octadecatrienoate, with racemic 6-, 10-, and 13-gamma-hydroperoxy-(10E,12Z,15Z)-octadecatrienoates as secondary products
-
-
?
linoleate + O2
-
705465
Solanum tuberosum
(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
98% (10E,12Z)-9-hydroperoxy-10,12-octadecadienoate, almost exclusively S stereoconfiguration. (9Z,11E,13S)-13-hydroperoxy-9,11-octadecadienoate is a minor byproduct
-
-
?
linoleate + O2
-
705465
Arabidopsis thaliana
(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
the main product (94%) is (10E,12Z)-9-hydroperoxy-10,12-octadecadienoate, primarily S configuration
-
-
?
additional information
low activity with arachidonate, the C20 fatty acid is converted into a mixture of racemic products
705465
Arabidopsis thaliana
?
-
-
-
-
additional information
low activity with arachidonate, the C20 fatty acid is converted into a mixture of racemic products
705465
Solanum tuberosum
?
-
-
-
-
Other publictions for EC 1.13.11.58
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742051
Roychowdhury
Functional characterization o ...
Oryza sativa, Oryza sativa Japonica Group
BioMed Res. Int.
2016
4275904
2016
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742627
Schiller
A dual positional specific li ...
Malus domestica
Hortic. Res.
2
15003-15015
2015
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742693
Rameshwari
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Computational analysis of tub ...
Solanum tuberosum
Int. J. ChemTech Res.
8
294-310
2015
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3
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743426
Zhou
The 9-lipoxygenase Osr9-LOX1 ...
Oryza sativa Japonica Group
Physiol. Plant.
152
59-69
2014
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725160
Li
A chitosan induced 9-lipoxygen ...
Cynanchum gracillimum
Int. J. Mol. Sci.
13
540-551
2012
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725794
Nam
Interactions among LOX metabol ...
Ipomoea nil, Ipomoea nil Choisy
J. Plant Physiol.
169
1815-1820
2012
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726018
Vicente
Role of 9-lipoxygenase and alp ...
Arabidopsis thaliana
Mol. Plant
5
914-928
2012
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3
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724660
Huang
Cloning and characterization o ...
Nicotiana benthamiana
BMC Biotechnol.
11
30
2011
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725855
Hamberg
Efficient and specific convers ...
Beta vulgaris
Lipids
46
873-878
2011
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706336
Hwang
The pepper 9-lipoxygenase gene ...
Capsicum annuum, Capsicum annuum Nockwang
Plant Physiol.
152
948-967
2010
-
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1
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2
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2
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11
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6
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1
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2
2
1
2
2
706392
Park
Comparative molecular and bioc ...
Zea mays
Planta
231
1425-1437
2010
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729971
Zheng
Dioxygenase activity of epider ...
Homo sapiens
J. Biol. Chem.
285
39866-39875
2010
1
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702392
Chechetkin
Specificity of oxidation of li ...
Zea mays
Biochemistry
74
855-861
2009
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705464
Boeglin
Investigation of substrate bin ...
Arabidopsis thaliana, Solanum lycopersicum
Lipids
43
979-987
2008
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705465
Andreou
On the substrate binding of li ...
Arabidopsis thaliana, Solanum tuberosum
Lipids
44
207-215
2008
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705472
Bannenberg
Diversity of the enzymatic act ...
Arabidopsis thaliana
Lipids
44
85-95
2008
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705809
Gao
Maize 9-lipoxygenase ZmLOX3 co ...
Zea mays
Mol. Plant Microbe Interact.
21
98-109
2008
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705807
Gao
Disruption of a maize 9-lipoxy ...
Zea mays
Mol. Plant Microbe Interact.
20
922-933
2007
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706206
Vellosillo
Oxylipins produced by the 9-li ...
Arabidopsis thaliana
Plant Cell
19
831-846
2007
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4
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706263
Marmey
The gene is associated with th ...
Gossypium hirsutum
Plant Physiol. Biochem.
45
596-606
2007
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1
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674121
Kuo
Lipoxygenase from banana leaf: ...
Musa acuminata
J. Agric. Food Chem.
54
3151-3156
2006
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674135
Garbe
Dual positional and stereospec ...
Hordeum vulgare
J. Agric. Food Chem.
54
946-955
2006
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