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Literature summary for 1.13.11.34 extracted from

  • Chen, T.; Shiao, M.; Pan, B.S.
    Inhibition of 12- and 15-lipoxygenase activities and protection of human and tilapia low density lipoprotein oxidation by I-Tiao-Gung (Glycine tomentella) (2005), Lipids, 40, 1171-1177.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information 95% ethanol extract of Glycine tomentella inhibits tilapia thrombocyte 5-LOX with IC50 of 0.00043 mg/ml Oreochromis niloticus
nordihydroguaiaretic acid IC50: 0.0023 mg/ml Oreochromis niloticus

Organism

Organism UniProt Comment Textmining
Oreochromis niloticus
-
tilapia
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet
-
Oreochromis niloticus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2
-
Oreochromis niloticus (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
?

Synonyms

Synonyms Comment Organism
5-LOX
-
Oreochromis niloticus