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Literature summary for 1.13.11.34 extracted from

  • Ghosh, J.
    Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase (2004), Biochem. Biophys. Res. Commun., 315, 624-635.
    View publication on PubMed

Application

Application Comment Organism
medicine selenium -induced apoptosis in prostate cancer cells may be mediated thgroufgh inhibition of the activity of arachidonate 5-lipoxygenase. The anti-cancer effects of selenium may be substantially compromised by consumption of high-fat diets rich in arachidonic acid or its precursor fatty acids Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information selenium-induced apoptosis in prostate cancer cells may be mediated through inhibition of the activity of arachidonate 5-lipoxygenase. The anti-cancer effects of selenium may be substantially compromised by consumption of high-fat diets rich in arachidonic acid or its precursor fatty acids Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
Homo sapiens
-