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Literature summary for 1.13.11.34 extracted from

  • Corey, E.J.; Casman, J.R.; Eckrich, T.M.; Corey, D.R.
    A new class of irreversible inhibitors of leukotriene biosynthesis (1985), J. Am. Chem. Soc., 107, 713-715.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
7-thiaarachidonic acid
-
Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
6-(trideca-1,4,7-triene-1-sulfinyl)-hex-5-enoic acid
-
Rattus norvegicus
6-ethenesulfinyl-hex-5-enoic acid
-
Rattus norvegicus
6-ethenesulfinyl-hex-5-enoic acid amide
-
Rattus norvegicus
6-hept-1-ene-1-sulfinyl-hex-5-enoic acid
-
Rattus norvegicus
6-hept-1-enylsulfanyl-hex-5-enoic acid
-
Rattus norvegicus
6-vinylsulfanyl-hex-5-enoic acid
-
Rattus norvegicus
6-vinylsulfanyl-hex-5-enoic acid amide
-
Rattus norvegicus
7-thiaarachidonic acid
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leukemia cell
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2 i.e. 5,8,11,14-eicosatetraenoic acid Rattus norvegicus (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
-
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