Literature summary for 1.13.11.34 extracted from

Wiseman, J.S.; Skoog, M.T.; Nichols, J.S.; Harrison, B.L.
Kinetics of leukotriene A4 synthesis by 5-lipoxygenase from rat polymorphonuclear leukocytes (1987), Biochemistry, 26, 5684-5689.

Search for more literature for 1.13.11.34

Inhibitors

Inhibitors	Comment	Organism	Structure
(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate	inhibits reaction with arachidonate	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leukocyte	polymorphonuclear	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate + O2	-	Rattus norvegicus	leukotriene A4	-	?
arachidonate + O2	i.e. 5,8,11,14-eicosatetraenoic acid	Rattus norvegicus	(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate	formation of leukotriene A4 without release of the intermediate (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)