Literature summary for 1.13.11.3 extracted from

Walsh, T.A.; Ballou, D.P.
Halogenated protocatechuates as substrates for protocatechuate dioxygenase from Pseudomonas cepacia (1983), J. Biol. Chem., 258, 14413-14421.

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Organism

Organism	UniProt	Comment	Textmining
Burkholderia cepacia	-	formerly classified as Pseudomonas cepacia	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3,4-dihydroxybenzoate + O2	very low activity with 2-chloro-protocatechuate	Burkholderia cepacia	3-carboxy-cis,cis-muconate	-	?
3,4-dihydroxybenzoate + O2	very low activity with 5-bromo-protocatechuate	Burkholderia cepacia	3-carboxy-cis,cis-muconate	-	?
3,4-dihydroxybenzoate + O2	very low activity with 5-chloro-protocatechuate	Burkholderia cepacia	3-carboxy-cis,cis-muconate	-	?
5-fluoro-protocatechuic acid + O2	at 2.1% the rate of protocatechuic acid oxidation	Burkholderia cepacia	5-fluoro-3-carboxy-cis,cis-muconate	-	?
6-chloro-protocatechuate + O2	at 4.3% the rate of protocatechuic acid oxidation	Burkholderia cepacia	6-chloro-3-carboxy-cis,cis-muconate	-	?

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Release 2023.1 (January 2023)