Cloned (Comment) | Organism |
---|---|
vaccinia virus-based expression in human AMA cells and expression in Escherichia coli | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxyphenylpyruvate + O2 | Homo sapiens | key enzyme involved in tyrosine catabolism, congenital 4-hydroxyphenylpyruvate dioxygenase deficiency is a rare, relatively benign condition known as hereditary type III tyrosinemia | homogentisate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | recombinant enzyme can be phosphorylated in human AMA cells, phosphorylation is not indispensable for activity | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
keratinocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxyphenylpyruvate + O2 | - |
Homo sapiens | homogentisate + CO2 | - |
? | |
4-hydroxyphenylpyruvate + O2 | key enzyme involved in tyrosine catabolism, congenital 4-hydroxyphenylpyruvate dioxygenase deficiency is a rare, relatively benign condition known as hereditary type III tyrosinemia | Homo sapiens | homogentisate + CO2 | - |
? |