Literature summary for 1.13.11.20 extracted from

Adams, M.A.; Shearer, G.
Cysteine dioxygenase enzyme activity and gene expression in the dimorphic pathogenic fungus Histoplasma capsulatum is in both the mold and yeast morphotypes and exhibits substantial strain variation (2020), J. Fungi (Basel), 6, 24 .

Search for more literature for 1.13.11.20

Organism

Organism	UniProt	Comment	Textmining
Histoplasma capsulatum	Q5RLY7	i.e. Ajellomyces capsulatus	-
Histoplasma capsulatum ATCC MYA-2454	Q5RLY7	i.e. Ajellomyces capsulatus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-cysteine + O2	-	Histoplasma capsulatum	3-sulfino-L-alanine	-	?
L-cysteine + O2	-	Histoplasma capsulatum ATCC MYA-2454	3-sulfino-L-alanine	-	?

Subunits

Subunits	Comment	Organism
?	x * 24700, SDS-PAGE, x * 23800, calculated from sequence	Histoplasma capsulatum

Synonyms

Synonyms	Comment	Organism
CDO1	-	Histoplasma capsulatum

Expression

Organism	Comment	Expression
Histoplasma capsulatum	CDO1 gene is expressed in both the mold and yeast morphotypes and both morphotypes show significant CDO activity	additional information

General Information

General Information	Comment	Organism
physiological function	CDO1 gene is expressed in both the mold and yeast morphotypes and both morphotypes show significant CDO activity. Intracellular cysteine levels are significantly higher in the mold form of two Panamanian strains, 184AS and 186AS, equal in both mold and yeast in the class 1 Downs strain and significantly higher in yeast of the more pathogenic class 2 G217B strain	Histoplasma capsulatum

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Release 2023.1 (January 2023)