Literature summary for 1.13.11.20 extracted from

Kwon, Y.H.; Stipanuk, M.H.
Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes (2001), Am. J. Physiol. Endocrinol. Metab., 280, E804-815.

Search for more literature for 1.13.11.20

Activating Compound

Activating Compound	Comment	Organism	Structure
DL-homocysteine	increases activity	Rattus norvegicus
L-cysteine	induces the enzyme	Rattus norvegicus
L-cysteine	acts as an initial signal for regulation of the enzyme, upregulates enzyme activity	Rattus norvegicus
methionine	induces	Rattus norvegicus
methionine	increases enzyme activity	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
DL-propargylglycine	reduces the enzyme activity in methionine-supplemented medium to the basal level, does not reduce the enzyme activity in cysteine-supplemented medium, no effect in hepatocytes cultured in basal medium	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
23500	-	detected by antibody for the enzyme	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	Sprague-Dawley strain male rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-cysteine + O2	-	Rattus norvegicus	3-sulfino-L-alanine	-	?

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Release 2023.1 (January 2023)