BRENDA - Enzyme Database show
show all sequences of 1.13.11.12

An iron 13S-lipoxygenase with an alpha-linolenic acid specific hydroperoxidase activity from Fusarium oxysporum

Brodhun, F.; Cristobal-Sarramian, A.; Zabel, S.; Newie, J.; Hamberg, M.; Feussner, I.; PLoS ONE 8, e64919 (2013)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
gene FoxLOX, DNA and amino acid sequence determination and analysis, phylogenetic analysis and sequence comparison, recombinnat expression of His-tagged enzyme
Fusarium oxysporum
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
Michaelis-Menten kinetics
Fusarium oxysporum
0.00337
-
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid
pH 8.0, 22°C
Fusarium oxysporum
0.00689
-
(9Z,12Z)-octadeca-9,12-dienoic acid
pH 8.0, 22°C
Fusarium oxysporum
0.0316
-
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid
pH 8.0, 22°C
Fusarium oxysporum
0.0348
-
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
pH 8.0, 22°C
Fusarium oxysporum
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Fe2+
weakly active site-bound, required for catalysis, non-heme iron lipoxygenase
Fusarium oxysporum
additional information
specifically binds iron but not manganese
Fusarium oxysporum
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
8500
-
2 * 8500, recombinant His-tagged enzyme, SDS-PAGE
Fusarium oxysporum
160000
-
about, recombinant His-tagged enzyme, gel filtration
Fusarium oxysporum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
linoleate + O2
Fusarium oxysporum
-
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
?
linoleate + O2
Fusarium oxysporum 4287
-
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
?
additional information
Fusarium oxysporum
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
?
-
-
-
additional information
Fusarium oxysporum 4287
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Fusarium oxysporum
-
f. sp. lycopersici
-
Fusarium oxysporum 4287
-
f. sp. lycopersici
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
mycelium
-
Fusarium oxysporum
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid + O2
-
726338
Fusarium oxysporum
?
-
-
-
?
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid + O2
-
726338
Fusarium oxysporum 4287
?
-
-
-
?
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid + O2
-
726338
Fusarium oxysporum
?
-
-
-
?
(9Z,12Z)-octadeca-9,12-dienoic acid + O2
-
726338
Fusarium oxysporum
?
-
-
-
?
(9Z,12Z)-octadeca-9,12-dienoic acid + O2
-
726338
Fusarium oxysporum 4287
?
-
-
-
?
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid + O2
-
726338
Fusarium oxysporum
(9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate
-
-
-
?
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid + O2
-
726338
Fusarium oxysporum 4287
(9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate
-
-
-
?
linoleate + O2
-
726338
Fusarium oxysporum
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
-
?
linoleate + O2
-
726338
Fusarium oxysporum 4287
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
-
?
additional information
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
726338
Fusarium oxysporum
?
-
-
-
-
additional information
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
726338
Fusarium oxysporum 4287
?
-
-
-
-
Subunits
Subunits
Commentary
Organism
homodimer
2 * 8500, recombinant His-tagged enzyme, SDS-PAGE
Fusarium oxysporum
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
22
-
assay at room temperaature
Fusarium oxysporum
Turnover Number [1/s]
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.566
-
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid
pH 8.0, 22°C
Fusarium oxysporum
1.71
-
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid
pH 8.0, 22°C
Fusarium oxysporum
2.611
-
(9Z,12Z)-octadeca-9,12-dienoic acid
pH 8.0, 22°C
Fusarium oxysporum
18.58
-
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
pH 8.0, 22°C
Fusarium oxysporum
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Fusarium oxysporum
pH Range
pH Minimum
pH Maximum
Commentary
Organism
7
10.5
activity range, overview. Low activity below pH 7.0, maximum activity at pH 8.0, 75% of maximal activity at up to pH 10.5
Fusarium oxysporum
Cloned(Commentary) (protein specific)
Commentary
Organism
gene FoxLOX, DNA and amino acid sequence determination and analysis, phylogenetic analysis and sequence comparison, recombinnat expression of His-tagged enzyme
Fusarium oxysporum
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
Michaelis-Menten kinetics
Fusarium oxysporum
0.00337
-
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid
pH 8.0, 22°C
Fusarium oxysporum
0.00689
-
(9Z,12Z)-octadeca-9,12-dienoic acid
pH 8.0, 22°C
Fusarium oxysporum
0.0316
-
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid
pH 8.0, 22°C
Fusarium oxysporum
0.0348
-
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
pH 8.0, 22°C
Fusarium oxysporum
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Fe2+
weakly active site-bound, required for catalysis, non-heme iron lipoxygenase
Fusarium oxysporum
additional information
specifically binds iron but not manganese
Fusarium oxysporum
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
8500
-
2 * 8500, recombinant His-tagged enzyme, SDS-PAGE
Fusarium oxysporum
160000
-
about, recombinant His-tagged enzyme, gel filtration
Fusarium oxysporum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
linoleate + O2
Fusarium oxysporum
-
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
?
linoleate + O2
Fusarium oxysporum 4287
-
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
?
additional information
Fusarium oxysporum
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
?
-
-
-
additional information
Fusarium oxysporum 4287
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
?
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
mycelium
-
Fusarium oxysporum
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid + O2
-
726338
Fusarium oxysporum
?
-
-
-
?
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid + O2
-
726338
Fusarium oxysporum 4287
?
-
-
-
?
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid + O2
-
726338
Fusarium oxysporum
?
-
-
-
?
(9Z,12Z)-octadeca-9,12-dienoic acid + O2
-
726338
Fusarium oxysporum
?
-
-
-
?
(9Z,12Z)-octadeca-9,12-dienoic acid + O2
-
726338
Fusarium oxysporum 4287
?
-
-
-
?
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid + O2
-
726338
Fusarium oxysporum
(9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate
-
-
-
?
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid + O2
-
726338
Fusarium oxysporum 4287
(9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate
-
-
-
?
linoleate + O2
-
726338
Fusarium oxysporum
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
-
?
linoleate + O2
-
726338
Fusarium oxysporum 4287
(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
-
-
-
?
additional information
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
726338
Fusarium oxysporum
?
-
-
-
-
additional information
product specificity of FoxLOX, by SP-HPLC/DAD analysis, overview
726338
Fusarium oxysporum 4287
?
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
homodimer
2 * 8500, recombinant His-tagged enzyme, SDS-PAGE
Fusarium oxysporum
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
22
-
assay at room temperaature
Fusarium oxysporum
Turnover Number [1/s] (protein specific)
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.566
-
(9Z,12Z,15Z)-9,12,15-octadecatrienoic acid
pH 8.0, 22°C
Fusarium oxysporum
1.71
-
(5Z,8Z,11Z,14Z)-eicosatetra-5,8,11,14-enoic acid
pH 8.0, 22°C
Fusarium oxysporum
2.611
-
(9Z,12Z)-octadeca-9,12-dienoic acid
pH 8.0, 22°C
Fusarium oxysporum
18.58
-
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
pH 8.0, 22°C
Fusarium oxysporum
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Fusarium oxysporum
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
7
10.5
activity range, overview. Low activity below pH 7.0, maximum activity at pH 8.0, 75% of maximal activity at up to pH 10.5
Fusarium oxysporum
General Information
General Information
Commentary
Organism
additional information
non-heme iron lipoxygenase oxidizes C18-polyunsaturated fatty acids to 13S-hydroperoxy derivatives by an antarafacial reaction mechanism where the bis-allylic hydrogen abstraction is the rate-limiting step
Fusarium oxysporum
General Information (protein specific)
General Information
Commentary
Organism
additional information
non-heme iron lipoxygenase oxidizes C18-polyunsaturated fatty acids to 13S-hydroperoxy derivatives by an antarafacial reaction mechanism where the bis-allylic hydrogen abstraction is the rate-limiting step
Fusarium oxysporum
Other publictions for EC 1.13.11.12
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
742050
Roychowdhury
Functional characterization o ...
Oryza sativa
BioMed Res. Int.
2016
0000
2016
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1
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1
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-
-
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-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
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-
-
-
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-
-
-
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-
-
-
1
-
-
-
-
-
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743601
Cao
Heterologous expression and b ...
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PLoS ONE
11
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-
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1
-
-
-
-
4
2
-
-
4
-
6
-
-
1
-
-
-
-
-
4
2
2
1
-
4
2
-
-
-
-
2
-
-
-
2
-
-
-
-
-
-
-
4
2
-
-
4
-
-
-
2
-
-
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-
4
4
2
2
-
4
2
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2
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4
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4
4
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Purification, characterizatio ...
Lasiodiplodia theobromae, Lasiodiplodia theobromae MTCC 3068
Appl. Biochem. Biotechnol.
175
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-
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-
-
-
-
1
1
-
-
2
2
-
5
-
-
1
-
-
1
2
-
2
1
2
1
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
2
2
-
-
-
1
-
1
2
-
2
1
2
1
-
-
1
-
-
-
-
1
1
-
-
-
741748
An
Characterization of an omega- ...
Burkholderia thailandensis, Burkholderia thailandensis KCTC 23190
Appl. Microbiol. Biotechnol.
99
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2015
1
1
1
-
-
-
5
5
-
5
1
7
-
5
-
-
1
-
-
-
4
-
11
1
1
1
1
4
1
1
-
-
-
-
-
1
1
1
-
-
-
-
-
5
-
5
-
5
1
7
-
-
-
1
-
-
4
-
11
1
1
1
1
4
1
1
-
-
-
1
1
-
4
4
741779
Banthiya
Secreted lipoxygenase from Ps ...
Pseudomonas aeruginosa
Arch. Biochem. Biophys.
584
116-124
2015
-
-
1
-
-
-
-
-
1
-
-
3
-
5
-
-
1
-
-
2
-
-
3
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
1
-
2
-
-
3
-
-
-
-
2
-
-
-
-
-
1
1
-
-
-
741974
Ogorodnikova
Stereospecific biosynthesis o ...
Zea mays
Biochim. Biophys. Acta
1851
1262-1270
2015
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
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-
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-
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-
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-
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-
-
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1
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
742627
Schiller
A dual positional specific li ...
Malus domestica
Hortic. Res.
2
15003-15015
2015
-
-
1
-
1
-
-
1
1
-
-
2
-
3
-
-
1
-
-
4
-
-
4
1
1
1
-
-
1
1
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
1
1
-
-
2
-
-
-
1
-
4
-
-
4
1
1
1
-
-
1
1
-
-
-
3
3
-
-
-
743426
Zhou
The 9-lipoxygenase Osr9-LOX1 ...
Gracilaria dura
Physiol. Plant.
152
59-69
2014
-
-
-
-
-
-
-
-
-
-
-
2
-
5
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
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-
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-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
1
1
1
-
-
724085
Lu
Overproduction, purification, ...
Pseudomonas aeruginosa, Pseudomonas aeruginosa BBE
Appl. Microbiol. Biotechnol.
97
5793-5800
2013
-
1
1
-
-
-
-
1
1
1
1
2
-
5
-
-
1
-
-
-
1
-
4
1
1
1
1
-
1
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
1
1
1
2
-
-
-
1
-
-
1
-
4
1
1
1
1
-
1
1
-
-
-
-
-
-
-
-
726182
Hu
-
Overexpression of the tomato 1 ...
Solanum lycopersicum
Plant Mol. Biol. Rep.
31
1141-1149
2013
-
1
1
-
1
-
-
-
-
-
-
3
-
1
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
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-
-
1
1
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
1
1
1
1
-
-
726338
Brodhun
An iron 13S-lipoxygenase with ...
Fusarium oxysporum, Fusarium oxysporum 4287
PLoS ONE
8
e64919
2013
-
-
1
-
-
-
-
5
-
2
2
4
-
8
-
-
-
-
-
1
-
-
11
1
1
-
-
4
1
1
-
-
-
-
-
-
-
1
-
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-
-
-
5
-
2
2
4
-
-
-
-
-
1
-
-
11
1
1
-
-
4
1
1
-
-
-
1
1
-
-
-
725794
Nam
Interactions among LOX metabol ...
Ipomoea nil, Ipomoea nil Choisy
J. Plant Physiol.
169
1815-1820
2012
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
2
-
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-
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-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
726126
Demchenko
Analysis of the subcellular lo ...
Casuarina glauca, Datisca glomerata
Plant Biol.
14
56-63
2012
-
-
-
-
-
-
-
-
4
-
-
4
-
6
-
-
-
-
-
6
-
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5
-
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-
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4
-
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-
-
6
-
-
5
-
-
-
-
-
-
-
-
-
-
4
4
-
-
-
724511
Chohany
Cationic substrates of soybean ...
Glycine max
Bioorg. Chem.
39
94-100
2011
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
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1
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-
-
3
-
1
-
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-
1
-
-
-
-
-
-
-
-
-
706007
Bruinsma
Inhibition of lipoxygenase aff ...
Brassica oleracea var. gemmifera
Oecologia
162
393-404
2010
-
-
-
-
-
-
1
-
-
-
-
-
-
8
-
-
-
-
-
-
-
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-
-
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-
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-
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-
-
-
-
-
-
-
-
-
-
711183
Osipova
Hexadecanoid pathway in plants ...
Glycine max
Biochemistry (Moscow)
75
708-716
2010
-
-
1
-
-
-
-
-
-
-
-
1
-
5
-
-
1
-
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2
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1
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-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
711631
Liu
Honokiol inhibits gastric tumo ...
Homo sapiens
Br. J. Pharmacol.
160
1963-1972
2010
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
4
-
-
1
-
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1
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-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
711723
Ha
Inhibition mode of soybean lip ...
Glycine max
Chem. Biodivers.
7
1893-1903
2010
-
-
-
-
-
-
5
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
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1
-
-
-
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-
1
5
-
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-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
711726
Rajic
The novel ketoprofen amides--s ...
Glycine max
Chem. Biol. Drug Des.
75
641-652
2010
-
-
-
-
-
-
30
-
-
-
-
-
-
2
-
-
-
-
-
-
-
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1
-
-
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-
-
-
-
-
-
-
-
29
-
-
-
-
-
-
-
29
30
-
-
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-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
712022
Keereetaweep
Lauroylethanolamide is a poten ...
Glycine max
FEBS Lett.
584
3215-3222
2010
-
-
-
-
-
-
2
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
2
8
4
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
712419
Zheng
Formation of a cyclopropyl epo ...
Glycine max
J. Biol. Chem.
285
13427-13436
2010
-
-
-
-
-
-
1
-
-
1
-
-
-
2
-
-
-
-
-
-
-
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3
-
-
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-
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1
-
-
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1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
712481
Zheng
On the role of molecular oxyge ...
Glycine max
J. Biol. Chem.
285
39876-39887
2010
1
-
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
-
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2
-
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1
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1
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-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
713248
Allmann
Oxylipin channelling in Nicoti ...
Nicotiana attenuata
Plant Cell Environ.
33
2028-2040
2010
-
-
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
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2
-
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2
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
1
1
1
2
-
-
702431
Palmieri-Thiers
A lipoxygenase with dual posit ...
Olea europaea
Biochim. Biophys. Acta
1791
339-346
2009
-
-
1
-
-
-
2
2
-
-
2
-
-
5
-
-
1
-
-
1
1
-
2
1
-
-
-
2
1
-
-
-
2
1
-
-
-
1
-
-
-
-
-
2
2
2
-
-
2
-
-
-
-
1
-
1
1
-
2
1
-
-
-
2
1
-
-
1
-
1
1
-
2
2
702635
Seyedi
Design, synthesis and SAR stud ...
Glycine max
Bioorg. Med. Chem.
17
1614-1622
2009
-
-
-
-
-
-
22
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
21
-
-
-
-
-
-
-
21
22
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
702638
Sadeghian
Design and synthesis of 4-meth ...
Glycine max
Bioorg. Med. Chem.
17
2327-2335
2009
-
-
-
-
-
-
20
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
19
-
-
-
-
-
-
-
19
20
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
702672
Detsi
Natural and synthetic 2-hydrox ...
Glycine max
Bioorg. Med. Chem.
17
8073-8085
2009
-
-
-
-
-
-
20
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
11
-
-
-
-
-
-
-
11
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
703036
Cimen
15-Lipoxygenase-1 expression s ...
Homo sapiens
Cancer Sci.
100
2283-2291
2009
-
1
1
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
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-
-
-
-
-
-
-
-
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-
-
1
1
-
-
-
-
-
1
-
-
-
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-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
704118
Pastore
New tool to evaluate a compreh ...
Glycine max
J. Agric. Food Chem.
28
9682-9292
2009
-
1
-
-
-
-
11
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
8
-
2
-
1
-
-
-
-
-
2
11
8
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
704142
Padilla
Functional characterization of ...
Olea europaea
J. Agric. Food Chem.
57
9097-9107
2009
-
-
1
-
-
-
3
8
2
1
2
-
-
4
-
-
1
-
-
4
-
-
4
-
2
1
-
-
4
-
-
-
-
2
-
-
-
1
-
-
-
-
-
3
-
8
2
1
2
-
-
-
-
1
-
4
-
-
4
-
2
1
-
-
4
-
-
2
1
1
1
1
1
1
705797
Knaup
Anthocyanins as lipoxygenase i ...
Glycine max
Mol. Nutr. Food Res.
53
617-624
2009
-
-
-
-
-
-
13
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
12
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
706678
Tamas
Effect of cadmium and temperat ...
Hordeum vulgare
Protoplasma
235
17-25
2009
-
-
-
-
-
-
1
-
3
1
-
-
-
3
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
1
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
1
1
1
1
-
-
701781
Horowitz Brown
Morphological transitions gove ...
Aspergillus flavus
Appl. Environ. Microbiol.
74
5674-5685
2008
-
-
-
-
1
-
-
-
-
1
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2
1
1
2
-
-
702550
Jacquot
Kinetic isotope effects in the ...
Glycine max
Bioorg. Med. Chem. Lett.
18
5959-5962
2008
-
-
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
705472
Bannenberg
Diversity of the enzymatic act ...
Arabidopsis thaliana
Lipids
44
85-95
2008
-
-
1
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
1
4
-
-
-
706032
Jacquot
Synthesis of 11-thialinoleic a ...
Glycine max
Org. Biomol. Chem.
6
4242-4252
2008
-
-
1
-
-
-
3
1
-
-
-
-
-
3
-
-
1
-
-
-
-
1
1
-
-
-
-
-
1
-
-
-
2
-
-
-
-
1
-
-
-
-
-
3
2
1
-
-
-
-
-
-
-
1
-
-
-
1
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
706121
Williams
Characterisation of lipoxygena ...
Olea europaea
Phytochemistry
69
2532-2538
2008
-
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
1
-
-
1
4
-
2
-
-
-
-
-
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
1
4
-
2
-
-
-
-
-
2
2
-
-
-
-
-
-
-
-
706122
Hornung
Identification of an amino aci ...
Momordica charantia
Phytochemistry
69
2774-2780
2008
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
706252
Wang
A novel lipoxygenase gene from ...
Oryza sativa
Plant Mol. Biol.
66
401-414
2008
-
1
1
-
-
-
-
-
1
-
1
-
-
5
-
-
1
-
-
3
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
1
-
3
-
-
1
1
-
-
-
-
1
-
-
-
2
1
1
2
-
-
706929
Kubo
Evaluation of lipoxygenase inh ...
Glycine max
Z. Naturforsch. C
63
539-546
2008
-
-
-
-
-
-
12
3
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
3
-
6
-
-
-
-
-
-
-
6
12
3
3
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
706116
Lang
Oxylipin formation in Nostoc p ...
Nostoc punctiforme
Phytochemistry
68
1120-1127
2007
-
-
1
-
-
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
4
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
4
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
674135
Garbe
Dual positional and stereospec ...
Hordeum vulgare
J. Agric. Food Chem.
54
946-955
2006
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703531
Vörös
Characterization of a methylja ...
Hordeum vulgare
Eur. J. Biochem.
251
36-44
1998
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703690
Feussner
All three acyl moieties of tri ...
Cucumis sativus
FEBS Lett.
431
433-436
1998
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704382
Royo
Characterization of three pota ...
Solanum tuberosum
J. Biol. Chem.
271
21012-21009
1996
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704379
Peng
A novel lipoxygenase from rice ...
Oryza sativa
J. Biol. Chem.
269
3755-3761
1994
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7
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