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Literature summary for 1.13.11.11 extracted from
- Acetylation of phenylalanine hydroxylase and tryptophan 2,3-dioxygenase alters hepatic aromatic amino acid metabolism in weaned piglets (2020), Metabolites, 10, 146 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan + O2 | Sus scrofa | - |
N-formyl-L-kynurenine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | F1RWA8 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| acetylation | weaning exacerbates the deacetylation of tryptophan 2,3-dioxygenase. Weaning alters the tryptophan 2,3-dioxygenase activity by affecting the acetylation state of the enzyme in piglets livers | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hepatocyte | - |
Sus scrofa | - |
| liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan + O2 | - |
Sus scrofa | N-formyl-L-kynurenine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TDO | - |
Sus scrofa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | weaning alters the tryptophan 2,3-dioxygenase activity by affecting the acetylation state of the enzyme in piglets livers | Sus scrofa |
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Release 2023.1 (January 2023)
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