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Literature summary for 1.11.1.8 extracted from

  • Habza-Kowalska, E.; Gawlik-Dziki, U.; Dziki, D.
    Mechanism of action and interactions between thyroid peroxidase and lipoxygenase inhibitors derived from plant sources (2019), Biomolecules, 9, 663 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
cumin ethanol extract activating, and also acts as effective lipoxygenase inhibitor Sus scrofa
green coffee ethanol extract activating, and also acts as effective lipoxygenase inhibitor Sus scrofa
green tea ethanol extract activating, and also acts as effective lipoxygenase inhibitor Sus scrofa
mustard ethanol extract activating, and also acts as effective lipoxygenase inhibitor Sus scrofa

Inhibitors

Inhibitors Comment Organism Structure
apigenin uncompetitive, IC50 value 0.406 mg/ml Sus scrofa
catechin competitive, IC50 value 0.078 mg/ml Sus scrofa
kaempferol competitive, IC50 value 0.337 mg/ml Sus scrofa
parsley ethanol extract
-
Sus scrofa
sinapinic acid competitive, IC50 value 0.084 mg/ml Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa P09933
-
-

Source Tissue

Source Tissue Comment Organism Textmining