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Literature summary for 1.11.1.25 extracted from

  • Couturier, J.
    Prosper, P.M.; Winger, A.M.; Hecker, A.; Hirasawa, M. Knaff, D.B.; Gans, P.; Jacquot, J.P.; Navaza, A.; Haouz, A.; Rouhier, N. In the absence of thioredoxins, what are the reductants for peroxiredoxins in Thermotoga maritima (2013), Antioxid. Redox Signal., 18, 1613-1622 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Thermotoga maritima

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.011
-
glutaredoxin 2 pH and temperature not specified in the publication Thermotoga maritima
0.0133
-
H2O2 pH and temperature not specified in the publication Thermotoga maritima
0.014
-
glutaredoxin 2 pH and temperature not specified in the publication Thermotoga maritima
0.018
-
glutaredoxin 3 pH and temperature not specified in the publication Thermotoga maritima
0.03
-
glutaredoxin 3 pH and temperature not specified in the publication Thermotoga maritima
0.0396
-
H2O2 pH and temperature not specified in the publication Thermotoga maritima

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
17300
-
calculated from sequence Thermotoga maritima
35000
-
gel filtration Thermotoga maritima
37200
-
calculated from sequence Thermotoga maritima
386000
-
gel filtration Thermotoga maritima

Organism

Organism UniProt Comment Textmining
Thermotoga maritima Q9WYL7
-
-
Thermotoga maritima Q9WZN7
-
-
Thermotoga maritima ATCC 43589 Q9WYL7
-
-
Thermotoga maritima ATCC 43589 Q9WZN7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutaredoxin + benzoquinone
-
Thermotoga maritima glutaredoxin disulfide + H2O + hydroquinone
-
?
glutaredoxin + benzoquinone
-
Thermotoga maritima ATCC 43589 glutaredoxin disulfide + H2O + hydroquinone
-
?
glutaredoxin 2 + H2O2
-
Thermotoga maritima glutaredoxin 2 disulfide + 2 H2O
-
?
glutaredoxin 2 + H2O2
-
Thermotoga maritima ATCC 43589 glutaredoxin 2 disulfide + 2 H2O
-
?
glutaredoxin 3 + H2O2
-
Thermotoga maritima glutaredoxin 3 disulfide + 2 H2O
-
?
glutaredoxin 3 + H2O2
-
Thermotoga maritima ATCC 43589 glutaredoxin 3 disulfide + 2 H2O
-
?

Subunits

Subunits Comment Organism
decamer 10 * 37200, calculated from sequence Thermotoga maritima
dimer 2 * 17300, calculated fromm sequence Thermotoga maritima

Synonyms

Synonyms Comment Organism
TM0780
-
Thermotoga maritima
TmPrxBCP
-
Thermotoga maritima
TmPrxNtr
-
Thermotoga maritima
TM_0386
-
Thermotoga maritima

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.12
-
H2O2 pH and temperature not specified in the publication Thermotoga maritima
0.27
-
H2O2 pH and temperature not specified in the publication Thermotoga maritima
52.8
-
benzoquinone pH and temperature not specified in the publication Thermotoga maritima

General Information

General Information Comment Organism
physiological function detoxification system, the enzyme prevents the damages caused by hydroperoxides Thermotoga maritima

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
3.1
-
H2O2 pH and temperature not specified in the publication Thermotoga maritima
20.3
-
H2O2 pH and temperature not specified in the publication Thermotoga maritima