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Literature summary for 1.11.1.25 extracted from

  • Pedrajas, J.R.; Padilla, C.A.; McDonagh, B.; Barcena, J.A.
    Glutaredoxin participates in the reduction of peroxides by the mitochondrial 1-CYS peroxiredoxin in Saccharomyces cerevisiae (2010), Antioxid. Redox Signal., 13, 249-258 .
    View publication on PubMed
Search for more literature for 1.11.1.25

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P34227
-
-
Saccharomyces cerevisiae ATCC 204508 P34227
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutaredoxin + H2O2
-
 Saccharomyces cerevisiae glutaredoxin disulfide + 2 H2O
-
 ?
glutaredoxin + H2O2
-
 Saccharomyces cerevisiae ATCC 204508 glutaredoxin disulfide + 2 H2O
-
 ?
glutaredoxin + tert-butyl hydroperoxide
-
 Saccharomyces cerevisiae glutaredoxin disulfide + H2O + tert-butyl alcohol
-
 ?
glutaredoxin + tert-butyl hydroperoxide
-
 Saccharomyces cerevisiae ATCC 204508 glutaredoxin disulfide + H2O + tert-butyl alcohol
-
 ?

Synonyms

Synonyms Comment Organism
glutaredoxin-dependent peroxidase
-
 Saccharomyces cerevisiae
Prx1
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
 Saccharomyces cerevisiae

pH Range

pH Minimum pH Maximum Comment Organism
7.5 9.3 pH 7.5: about 50% of maximal activity, pH 9.3: about 55% of maximal activity, substrate: tert-butyl hydroperoxide Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function reduction of peroxides by mitochondrial Prx1 is of importance to protect this organelle from oxidative stress Saccharomyces cerevisiae