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Literature summary for 1.11.1.23 extracted from

  • Milaczewska, A.; Broclawik, E.; Borowski, T.
    On the catalytic mechanism of (S)-2-hydroxypropylphosphonic acid epoxidase (HppE): a hybrid DFT study (2013), Chemistry, 19, 771-781.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ required Streptomyces wedmorensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-2-hydroxypropylphosphonate + H2O2 Streptomyces wedmorensis
-
2-oxopropylphosphonic acid + H2O
-
?
(S)-2-hydroxypropylphosphonate + H2O2 Streptomyces wedmorensis
-
(1R,2S)-1,2-epoxypropylphosphonate + H2O
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces wedmorensis Q56185
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-2-hydroxypropylphosphonate + H2O2
-
Streptomyces wedmorensis 2-oxopropylphosphonic acid + H2O
-
?
(S)-2-hydroxypropylphosphonate + H2O2
-
Streptomyces wedmorensis (1R,2S)-1,2-epoxypropylphosphonate + H2O
-
?

Synonyms

Synonyms Comment Organism
(S)-2-hydroxypropylphosphonic acid epoxidase
-
Streptomyces wedmorensis
HppE
-
Streptomyces wedmorensis

Cofactor

Cofactor Comment Organism Structure
FMN
-
Streptomyces wedmorensis
NAD(P)H
-
Streptomyces wedmorensis