Crystallization (Comment) | Organism |
---|---|
crystal structure of the D141E variant determined at 1.8 A resolution | Burkholderia pseudomallei |
Protein Variants | Comment | Organism |
---|---|---|
D141A | mutant with reduced catalase activity | Burkholderia pseudomallei |
D141E | mutant with normal catalase activity but with modified kinetics | Burkholderia pseudomallei |
R108A | mutant with reduced catalase activity | Burkholderia pseudomallei |
R108A/D141A | activity is 18% lower than wild-type activity | Burkholderia pseudomallei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Burkholderia pseudomallei | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2O2 | it is proposed that binding of substrate H2O2 to Asp141 and Arg108 controls H2O2 access to the heme active site, thereby modulating the catalase reaction | Burkholderia pseudomallei | O2 + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
catalase -peroxidase KatG | - |
Burkholderia pseudomallei |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | it is proposed that binding of substrate H2O2 to Asp141 and Arg108 controls H2O2 access to the heme active site, thereby modulating the catalase reaction | Burkholderia pseudomallei |