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Literature summary for 1.11.1.12 extracted from

  • Conrad, M.; Schneider, M.; Seiler, A.; Bornkamm, G.W.
    Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals (2007), Biol. Chem., 388, 1019-1025.
    View publication on PubMed
Search for more literature for 1.11.1.12

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Sus scrofa PhGPx prevents NF-kappaB activation, oxLDL-induced proliferation and linoleic acid-induced apoptosis ?
-
 ?
additional information Mus musculus PHGPx-/- mice are embryonically lethal at gestation day 7.5. PHGPx+/- mice cells show decreased life span after exposure to irradiation and increased susceptibility to oxidative and genotoxic stress ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PhGPx prevents NF-kappaB activation, oxLDL-induced proliferation and linoleic acid-induced apoptosis Sus scrofa ?
-
 ?
additional information PHGPx-/- mice are embryonically lethal at gestation day 7.5. PHGPx+/- mice cells show decreased life span after exposure to irradiation and increased susceptibility to oxidative and genotoxic stress Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
PHGPX
-
 Mus musculus
PHGPX
-
 Homo sapiens
PHGPX
-
 Rattus norvegicus
PHGPX
-
 Sus scrofa
phospholipid hydroperoxide glutathione peroxidase
-
 Mus musculus
phospholipid hydroperoxide glutathione peroxidase
-
 Homo sapiens
phospholipid hydroperoxide glutathione peroxidase
-
 Rattus norvegicus
phospholipid hydroperoxide glutathione peroxidase
-
 Sus scrofa