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Literature summary for 1.11.1.12 extracted from

  • Foresta, C.; Flohe, L.; Garolla, A.; Roveri, A.; Ursini, F.; Maiorino, M.
    Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase (2002), Biol. Reprod., 67, 967-971.
    View publication on PubMed

Application

Application Comment Organism
analysis because the content of enzyme, irrespective of the cause of alteration, is correlated with fertility-related parameters, PHGPx can be considered a predictive measure for fertilization capacity Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
selenium selenoprotein Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme appears to be indispensable for structural integrity of spermatozoa and to codetermine sperm motility and viability ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sperm enzyme is transformed to an oxidatively inactivated protein in mature sperm, where it is a major constituent of the mitochondrial capsule in the midpiece Homo sapiens
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spermatid enzyme is expressed as active peroxidase Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme appears to be indispensable for structural integrity of spermatozoa and to codetermine sperm motility and viability Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PHGPX
-
Homo sapiens
phospholipid hydroperoxide glutathione peroxidase
-
Homo sapiens