BRENDA - Enzyme Database show
show all sequences of 1.10.1.1

Dehydrogenation of trans-acenaphthene-1,2-diol by liver cytosol preparations

Hopkins, R.P.; Drummond, E.C.; Callaghan, P.; Biochem. Soc. Trans. 1, 989-991 (1973)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
ethanol
activation
Rattus norvegicus
Inhibitors
Inhibitors
Commentary
Organism
Structure
(+)-trans-Acenaphthene-1,2-diol
-
Rattus norvegicus
2,4-Dichlorophenol
75% inhibition at 1 mM
Rattus norvegicus
catechol
75% inhibition at 1 mM
Rattus norvegicus
Hg2+
100% inhibition at 0.1 mM
Rattus norvegicus
KCN
70% inhibition at 5 mM
Rattus norvegicus
NADPH
-
Rattus norvegicus
p-chloromercuribenzoate
100% inhibition at 0.25 mM
Rattus norvegicus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Canis lupus familiaris
5829
-
cytosol
-
Cavia porcellus
5829
-
cytosol
-
Felis catus
5829
-
cytosol
-
Mesocricetus auratus
5829
-
cytosol
-
Mus musculus
5829
-
cytosol
-
Oryctolagus cuniculus
5829
-
cytosol
-
Rattus norvegicus
5829
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mg2+
activation
Rattus norvegicus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(-)-trans-acenaphthene-1,2-diol + NADP+
Cavia porcellus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Mus musculus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Oryctolagus cuniculus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Canis lupus familiaris
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Mesocricetus auratus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Felis catus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Rattus norvegicus
inactive with (+)-form
acenaphthenequinone + NADPH
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Canis lupus familiaris
-
-
-
Cavia porcellus
-
-
-
Felis catus
-
-
-
Mesocricetus auratus
-
-
-
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-
Purification (Commentary)
Commentary
Organism
-
Rattus norvegicus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Canis lupus familiaris
-
liver
-
Cavia porcellus
-
liver
-
Felis catus
-
liver
-
Mesocricetus auratus
-
liver
-
Mus musculus
-
liver
-
Oryctolagus cuniculus
-
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
-
Canis lupus familiaris
additional information
-
-
Cavia porcellus
additional information
-
-
Felis catus
additional information
-
-
Mesocricetus auratus
additional information
-
-
Mus musculus
additional information
-
-
Oryctolagus cuniculus
additional information
-
-
Rattus norvegicus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Cavia porcellus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Mus musculus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Oryctolagus cuniculus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Canis lupus familiaris
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Mesocricetus auratus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Felis catus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
inactive with (+)-form
396338
Rattus norvegicus
acenaphthenequinone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Cavia porcellus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Mus musculus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Rattus norvegicus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Oryctolagus cuniculus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Canis lupus familiaris
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Mesocricetus auratus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Felis catus
1-acenaphthenone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Cavia porcellus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Mus musculus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Rattus norvegicus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Oryctolagus cuniculus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Canis lupus familiaris
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Mesocricetus auratus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Felis catus
1,2-naphthoquinone + NADPH
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
NADP+
inactive with NAD+
Rattus norvegicus
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
ethanol
activation
Rattus norvegicus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADP+
inactive with NAD+
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
(+)-trans-Acenaphthene-1,2-diol
-
Rattus norvegicus
2,4-Dichlorophenol
75% inhibition at 1 mM
Rattus norvegicus
catechol
75% inhibition at 1 mM
Rattus norvegicus
Hg2+
100% inhibition at 0.1 mM
Rattus norvegicus
KCN
70% inhibition at 5 mM
Rattus norvegicus
NADPH
-
Rattus norvegicus
p-chloromercuribenzoate
100% inhibition at 0.25 mM
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Canis lupus familiaris
5829
-
cytosol
-
Cavia porcellus
5829
-
cytosol
-
Felis catus
5829
-
cytosol
-
Mesocricetus auratus
5829
-
cytosol
-
Mus musculus
5829
-
cytosol
-
Oryctolagus cuniculus
5829
-
cytosol
-
Rattus norvegicus
5829
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mg2+
activation
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(-)-trans-acenaphthene-1,2-diol + NADP+
Cavia porcellus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Mus musculus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Oryctolagus cuniculus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Canis lupus familiaris
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Mesocricetus auratus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Felis catus
-
acenaphthenequinone + NADPH
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
Rattus norvegicus
inactive with (+)-form
acenaphthenequinone + NADPH
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Canis lupus familiaris
-
liver
-
Cavia porcellus
-
liver
-
Felis catus
-
liver
-
Mesocricetus auratus
-
liver
-
Mus musculus
-
liver
-
Oryctolagus cuniculus
-
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
-
Canis lupus familiaris
additional information
-
-
Cavia porcellus
additional information
-
-
Felis catus
additional information
-
-
Mesocricetus auratus
additional information
-
-
Mus musculus
additional information
-
-
Oryctolagus cuniculus
additional information
-
-
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Cavia porcellus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Mus musculus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Oryctolagus cuniculus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Canis lupus familiaris
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Mesocricetus auratus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
-
396338
Felis catus
acenaphthenequinone + NADPH
-
-
-
?
(-)-trans-acenaphthene-1,2-diol + NADP+
inactive with (+)-form
396338
Rattus norvegicus
acenaphthenequinone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Cavia porcellus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Mus musculus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Rattus norvegicus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Oryctolagus cuniculus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Canis lupus familiaris
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Mesocricetus auratus
1-acenaphthenone + NADPH
-
-
-
?
1-acenaphthenol + NADP+
-
396338
Felis catus
1-acenaphthenone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Cavia porcellus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Mus musculus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Rattus norvegicus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Oryctolagus cuniculus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Canis lupus familiaris
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Mesocricetus auratus
1,2-naphthoquinone + NADPH
-
-
-
?
trans-1,2-dihydronaphthalene-1,2-diol + NADP+
-
396338
Felis catus
1,2-naphthoquinone + NADPH
-
-
-
?
Other publictions for EC 1.10.1.1
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
396338
Hopkins
-
Dehydrogenation of trans-acena ...
Canis lupus familiaris, Cavia porcellus, Felis catus, Mesocricetus auratus, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus
Biochem. Soc. Trans.
1
989-991
1973
1
-
-
-
-
-
7
-
7
1
-
7
-
7
-
-
1
-
-
7
7
-
21
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
7
-
-
7
1
-
7
-
-
-
1
-
7
7
-
21
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
396339
Drummond
Metabolic dehydrogenation of c ...
Rattus norvegicus
Xenobiotica
2
529-538
1972
-
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1
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1
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1
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