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Literature summary for 1.1.99.41 extracted from

  • Qu, Y.; Easson, M.L.; Froese, J.; Simionescu, R.; Hudlicky, T.; De Luca, V.
    Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast (2015), Proc. Natl. Acad. Sci. USA, 112, 6224-6229 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.99.41

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
16-methoxytabersonine + NADPH + H+ Catharanthus roseus
-
 3-hydroxy-16-methoxy-2,3-dihydrotabersonine
-
 ?
tabersonine + NADPH + H+ Catharanthus roseus
-
 2,3-dihydro-3-hydroxytabersonine + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Catharanthus roseus A0A161CAI1 cultivar Little Delicata
-

Source Tissue

Source Tissue Comment Organism Textmining
epidermis
-
 Catharanthus roseus
-
leaf
-
 Catharanthus roseus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
16-hydroxytabersonine + NADPH + H+
-
 Catharanthus roseus ?
-
 ?
16-methoxytabersonine + NADPH + H+
-
 Catharanthus roseus 3-hydroxy-16-methoxy-2,3-dihydrotabersonine
-
 ?
2,3-dihydrotabersonine + NADPH + H+
-
 Catharanthus roseus ?
-
 ?
tabersonine + NADPH + H+
-
 Catharanthus roseus 2,3-dihydro-3-hydroxytabersonine + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
ADHL1
-
 Catharanthus roseus
T3R
-
 Catharanthus roseus
tabersonine 3-reductas
-
 Catharanthus roseus