Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
iron-sulfur center | in its active form, the enzyme contains an iron-sulfur center and an oxygen-sensitive glycyl radical (Gly681) | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P28903 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ribonucleoside 5'-triphosphate + formate | - |
Escherichia coli | 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O | in its active form, the enzyme contains an iron-sulfur center and an oxygen-sensitive glycyl radical (Gly681). The radical is generated in the inactive protein from S-adenosylmethionine by an auxiliary enzyme system. During catalysis, formate is stoichiometrically oxidized to CO2, and isotope from [3H]formate appears in water | ? |