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Literature summary for 1.1.5.3 extracted from

  • Pecinova, A.; Alan, L.; Brazdova, A.; Vrbacky, M.; Pecina, P.; Drahota, Z.; Houstek, J.; Mracek, T.
    Role of mitochondrial glycerol-3-phosphate dehydrogenase in metabolic adaptations of prostate cancer (2020), Cells, 9, 1764 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.5.3

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
140000
-
 PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P43304
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification the 42 amino acid presequence is cleaved from N-terminus during mGPDH biogenesis. Only the processed form is part of the mGPDH dimer that is the prominent functional enzyme entity Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-
PNT-1A cell
-
 Homo sapiens
-

Subunits

Subunits Comment Organism
dimer 2 * 70000, calculated from sequence Homo sapiens

Synonyms

Synonyms Comment Organism
GPD2
-
 Homo sapiens
mGPDH
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function mGPDH overexpression enhances the wound healing ability in prostate cancer cells Homo sapiens