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Literature summary for 1.1.5.3 extracted from

  • Skodova, I.; Verner, Z.; Bringaud, F.; Fabian, P.; Lukes, J.; Horvatha, A.
    Characterization of two mitochondrial flavin adenine dinucleotide-dependent glycerol-3-phosphate dehydrogenases in Trypanosoma brucei (2013), Eukaryot. Cell, 12, 1664-1673.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.5.3

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Trypanosoma brucei 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sn-glycerol 3-phosphate + a quinone Trypanosoma brucei
-
 glycerone phosphate + a quinol
-
 ?
sn-glycerol 3-phosphate + a quinone Trypanosoma brucei 29-13
-
 glycerone phosphate + a quinol
-
 ?

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei
-
-
-
Trypanosoma brucei 29-13
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DL-glycerol 3-phosphate + oxidized 2,6-dichlorophenolindophenol
-
 Trypanosoma brucei dihydroxyacetone phosphate + reduced 2,6-dichlorophenolindophenol
-
 ?
DL-glycerol 3-phosphate + oxidized 2,6-dichlorophenolindophenol
-
 Trypanosoma brucei 29-13 dihydroxyacetone phosphate + reduced 2,6-dichlorophenolindophenol
-
 ?
sn-glycerol 3-phosphate + a quinone
-
 Trypanosoma brucei glycerone phosphate + a quinol
-
 ?
sn-glycerol 3-phosphate + a quinone
-
 Trypanosoma brucei 29-13 glycerone phosphate + a quinol
-
 ?

Synonyms

Synonyms Comment Organism
FAD-G3PDH
-
 Trypanosoma brucei
flavin adenine dinucleotide-dependent glycerol-3-phosphate dehydrogenase
-
 Trypanosoma brucei
mtG3PDH isoform Trypanosoma brucei
putG3PDH isoform Trypanosoma brucei

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Trypanosoma brucei

General Information

General Information Comment Organism
physiological function isoform mtG3PDH is essential for the bloodstream stage of Trypanosoma brucei, while in the procyclic stage the enzyme is dispensable Trypanosoma brucei