BRENDA - Enzyme Database
show all sequences of 1.1.3.40

Histochemical and biochemical localization of mannitol oxidase in the snail Helix aspersa

Vorhaben, J.E.; Smith, D.D., Jr.; Campbell, J.W.; J. Exp. Zool. 231, 157-160 (1984)
No PubMed abstract available

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
Golgi membrane
associated with inner wall surrounding the lumen; membrane-bound
Helix aspersa
139
-
mitochondrion
-
Helix aspersa
5739
-
mitochondrion
-
Biomphalaria glabrata
5739
-
additional information
histochemical and biochemical localization
Helix aspersa
-
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
D-mannitol + O2
Biomphalaria glabrata
-
mannose + H2O2
-
-
?
D-mannitol + O2
Helix aspersa
mannitol oxidase plays an active role in the utilization of dietary mannitol
mannose + H2O2
-
-
?
additional information
Helix aspersa
naturally occuring polyols may be of nutritional value to herbivorous gastropod mollusc, mannitol oxidase plays a role in the metabolism of dietary sugar alcohols, gastropod molluscs derive nutritional benefit from ingestion of naturally orrurring polyols
?
-
-
-
Organism
Organism
UniProt
Commentary
Textmining
Biomphalaria glabrata
-
aquatic snail, low levels
-
Helix aspersa
-
common garden snail; terrestrial snail
-
Purification (Commentary)
Purification (Commentary)
Organism
partial
Helix aspersa
Source Tissue
Source Tissue
Commentary
Organism
Textmining
alimentary canal
-
Helix aspersa
-
columella muscle
very poor
Helix aspersa
-
crop
highest activity
Helix aspersa
-
digestive gland
-
Biomphalaria glabrata
-
digestive gland
hepatopancreas; substantial activity
Helix aspersa
-
esophagus
highest activity
Helix aspersa
-
excretory gland
substantial activity
Helix aspersa
-
foot muscle
very poor
Helix aspersa
-
gut
-
Helix aspersa
-
intestine
-
Helix aspersa
-
mantle cavity
-
Helix aspersa
-
additional information
enzyme concentrated within alimentary canal and digestive gland with highest specific activity in crop; not in albumen gland, buccal mass, heart and hemolymph; tissue distribution
Helix aspersa
-
ovotestis
-
Helix aspersa
-
reproductive system
poor
Helix aspersa
-
stomach
substantial activity
Helix aspersa
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
0.0137
-
esophagus and crop
Helix aspersa
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
D-arabinitol + O2
-
287631
Helix aspersa
arabinose + H2O2
-
-
-
?
D-mannitol + O2
-
287631
Helix aspersa
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287631
Biomphalaria glabrata
mannose + H2O2
-
-
-
?
D-mannitol + O2
mannitol oxidase plays an active role in the utilization of dietary mannitol
287631
Helix aspersa
mannose + H2O2
-
-
-
?
additional information
substrate specificity
287631
Helix aspersa
?
-
-
-
-
additional information
activity only with acyclic polyols
287631
Helix aspersa
?
-
-
-
-
additional information
L-arabinitol: not a substrate
287631
Helix aspersa
?
-
-
-
-
additional information
naturally occuring polyols may be of nutritional value to herbivorous gastropod mollusc, mannitol oxidase plays a role in the metabolism of dietary sugar alcohols, gastropod molluscs derive nutritional benefit from ingestion of naturally orrurring polyols
287631
Helix aspersa
?
-
-
-
-
Temperature Optimum [C]
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
25
-
assay at
Helix aspersa
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
assay at
Helix aspersa
Cofactor
Cofactor
Commentary
Organism
Structure
additional information
pyridine-nucleotide-independent
Helix aspersa
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
additional information
pyridine-nucleotide-independent
Helix aspersa
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
Golgi membrane
associated with inner wall surrounding the lumen; membrane-bound
Helix aspersa
139
-
mitochondrion
-
Helix aspersa
5739
-
mitochondrion
-
Biomphalaria glabrata
5739
-
additional information
histochemical and biochemical localization
Helix aspersa
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
D-mannitol + O2
Biomphalaria glabrata
-
mannose + H2O2
-
-
?
D-mannitol + O2
Helix aspersa
mannitol oxidase plays an active role in the utilization of dietary mannitol
mannose + H2O2
-
-
?
additional information
Helix aspersa
naturally occuring polyols may be of nutritional value to herbivorous gastropod mollusc, mannitol oxidase plays a role in the metabolism of dietary sugar alcohols, gastropod molluscs derive nutritional benefit from ingestion of naturally orrurring polyols
?
-
-
-
Purification (Commentary) (protein specific)
Commentary
Organism
partial
Helix aspersa
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
alimentary canal
-
Helix aspersa
-
columella muscle
very poor
Helix aspersa
-
crop
highest activity
Helix aspersa
-
digestive gland
-
Biomphalaria glabrata
-
digestive gland
hepatopancreas; substantial activity
Helix aspersa
-
esophagus
highest activity
Helix aspersa
-
excretory gland
substantial activity
Helix aspersa
-
foot muscle
very poor
Helix aspersa
-
gut
-
Helix aspersa
-
intestine
-
Helix aspersa
-
mantle cavity
-
Helix aspersa
-
additional information
enzyme concentrated within alimentary canal and digestive gland with highest specific activity in crop; not in albumen gland, buccal mass, heart and hemolymph; tissue distribution
Helix aspersa
-
ovotestis
-
Helix aspersa
-
reproductive system
poor
Helix aspersa
-
stomach
substantial activity
Helix aspersa
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
0.0137
-
esophagus and crop
Helix aspersa
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
D-arabinitol + O2
-
287631
Helix aspersa
arabinose + H2O2
-
-
-
?
D-mannitol + O2
-
287631
Helix aspersa
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287631
Biomphalaria glabrata
mannose + H2O2
-
-
-
?
D-mannitol + O2
mannitol oxidase plays an active role in the utilization of dietary mannitol
287631
Helix aspersa
mannose + H2O2
-
-
-
?
additional information
substrate specificity
287631
Helix aspersa
?
-
-
-
-
additional information
activity only with acyclic polyols
287631
Helix aspersa
?
-
-
-
-
additional information
L-arabinitol: not a substrate
287631
Helix aspersa
?
-
-
-
-
additional information
naturally occuring polyols may be of nutritional value to herbivorous gastropod mollusc, mannitol oxidase plays a role in the metabolism of dietary sugar alcohols, gastropod molluscs derive nutritional benefit from ingestion of naturally orrurring polyols
287631
Helix aspersa
?
-
-
-
-
Temperature Optimum [C] (protein specific)
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
25
-
assay at
Helix aspersa
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
assay at
Helix aspersa
Other publictions for EC 1.1.3.40
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
655277
Knigge
Mannosomes: a molluscan intrac ...
Arion lusitanicus
Comp. Biochem. Physiol. C
131
259-269
2002
-
-
-
-
-
-
3
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287633
Large
-
Centrifugal evidence for assoc ...
Arion ater, Arion lusitanicus, Helix aspersa, Limax flavus
Comp. Biochem. Physiol. A
107
621-629
1994
-
-
-
-
-
-
-
10
7
-
-
4
-
4
-
-
-
-
-
7
-
-
25
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
10
7
-
-
4
-
-
-
-
-
7
-
-
25
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
287630
Large
-
The association of mannitol ox ...
Arion ater
Protoplasma
175
93-101
1993
-
-
-
-
-
-
-
-
2
-
-
2
-
1
-
-
-
-
-
1
-
-
3
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
1
-
-
3
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287632
Malik
-
Assay and subcellular localiza ...
Arion ater
J. Exp. Zool.
242
9-15
1987
-
-
-
-
-
-
-
1
4
-
-
2
-
1
-
-
-
-
-
4
1
-
3
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
4
-
-
2
-
-
-
-
-
4
1
-
3
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
287629
Vorhaben
Mannitol oxidase: partial puri ...
Helix aspersa
Int. J. Biochem.
18
337-344
1986
1
-
-
-
-
2
3
2
2
-
1
2
-
2
-
1
1
1
-
5
1
3
16
2
-
1
-
-
-
2
1
2
1
-
-
-
1
-
-
1
-
-
2
-
3
-
2
2
-
1
2
-
-
1
1
-
5
1
3
16
2
1
-
-
-
2
1
2
-
-
-
-
-
-
-
287631
Vorhaben
-
Histochemical and biochemical ...
Biomphalaria glabrata, Helix aspersa
J. Exp. Zool.
231
157-160
1984
-
-
-
-
-
-
-
-
4
-
-
3
-
2
-
-
1
-
-
15
1
-
8
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
4
-
-
3
-
-
-
1
-
15
1
-
8
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-