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Literature summary for 1.1.3.17 extracted from

  • Hatefi, Y.; Stiggall, D.L.
    Metal-containing flavoprotein dehydrogenases (1976), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 13, 175-297.
No PubMed abstract available
Search for more literature for 1.1.3.17

Activating Compound

Activating Compound Comment Organism Structure
NAD+ stimulation of choline oxidation Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
2-chloro-N-(2-chloroethyl)-N-methylethanamine nitrogen mustard, strong competitive inhibitor Rattus norvegicus
Amytal
-
 Rattus norvegicus
Betaine aldehyde
-
 Rattus norvegicus
rotenone
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
7
-
 choline at 38°C and pH 7.6 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion membrane-bound Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
choline + O2 Rattus norvegicus
-
 betaine aldehyde + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rat
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
choline + O2
-
 Rattus norvegicus betaine aldehyde + H2O2
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2
-
 Betaine aldehyde oxidation of choline is competitively inhibited Rattus norvegicus