BRENDA - Reference to 1.1.2.3; Id = 348077

in Escherichia coli MM294

Saccharomyces cerevisiae

Y254F

only traces of activity

Saccharomyces cerevisiae

Y254L

turnover reduced to less than 10%

Saccharomyces cerevisiae

D-lactate

-

Saccharomyces cerevisiae

L-Mandelate

competitive

Saccharomyces cerevisiae

oxalate

-

Saccharomyces cerevisiae

pyruvate

competitive at low concentrations, non-competitve at high concentrations

Saccharomyces cerevisiae

sulfite

competitive

Saccharomyces cerevisiae

mitochondrial intermembrane space

-

Saccharomyces cerevisiae

5758

-

Fe2+

bound to enzyme

Saccharomyces cerevisiae

(S)-lactate + 2 ferricytochrome c

Saccharomyces cerevisiae

can feed electrons to respiratory chain at the level of cytochrome c

pyruvate + 2 ferrocytochrome c + 2 H+

-

Saccharomyces cerevisiae

-

Saccharomyces cerevisiae

-

Saccharomyces cerevisiae

(S)-lactate + 2 ferricytochrome c

-

348077

Saccharomyces cerevisiae

pyruvate + 2 ferrocytochrome c + 2 H+

-

348077

Saccharomyces cerevisiae

-

(S)-lactate + 2 ferricytochrome c

can feed electrons to respiratory chain at the level of cytochrome c

348077

Saccharomyces cerevisiae

pyruvate + 2 ferrocytochrome c + 2 H+

-

348077

Saccharomyces cerevisiae

-

additional information

ferricyanide used as electron acceptor

348077

Saccharomyces cerevisiae

?

-

additional information

electron acceptors other than ferricytochrome c used

348077

Saccharomyces cerevisiae

?

-

additional information

electron acceptors other than ferricytochrome c used; ferricyanide used as electron acceptor

Saccharomyces cerevisiae

in Escherichia coli MM294

Saccharomyces cerevisiae

additional information

electron acceptors other than ferricytochrome c used; ferricyanide used as electron acceptor

Saccharomyces cerevisiae

Y254F

only traces of activity

Saccharomyces cerevisiae

Y254L

turnover reduced to less than 10%

Saccharomyces cerevisiae

D-lactate

-

Saccharomyces cerevisiae

L-Mandelate

competitive

Saccharomyces cerevisiae

oxalate

-

Saccharomyces cerevisiae

pyruvate

competitive at low concentrations, non-competitve at high concentrations

Saccharomyces cerevisiae

sulfite

competitive

Saccharomyces cerevisiae

mitochondrial intermembrane space

-

Saccharomyces cerevisiae

5758

-

Fe2+

bound to enzyme

Saccharomyces cerevisiae

(S)-lactate + 2 ferricytochrome c

Saccharomyces cerevisiae

can feed electrons to respiratory chain at the level of cytochrome c

pyruvate + 2 ferrocytochrome c + 2 H+

-

Saccharomyces cerevisiae

-

Saccharomyces cerevisiae

(S)-lactate + 2 ferricytochrome c

-

348077

Saccharomyces cerevisiae

pyruvate + 2 ferrocytochrome c + 2 H+

-

348077

Saccharomyces cerevisiae

-

(S)-lactate + 2 ferricytochrome c

can feed electrons to respiratory chain at the level of cytochrome c

348077

Saccharomyces cerevisiae

pyruvate + 2 ferrocytochrome c + 2 H+

-

348077

Saccharomyces cerevisiae

-

additional information

ferricyanide used as electron acceptor

348077

Saccharomyces cerevisiae

?

-

additional information

electron acceptors other than ferricytochrome c used

348077

Saccharomyces cerevisiae

?

-

743420

Gillet

QM/MM study of l-lactate oxid ...

Saccharomyces cerevisiae

Phys. Chem. Chem. Phys.

18

15609-15618

2016

-

3

-

1

-

1

-

1

-

1

-

2

1

-

3

1

-

5

-

5

-

3

-

1

-

1

-

2

1

-

3

1

-

1

-

743494

Engqvist

Glycolate oxidase3, a glycola ...

Arabidopsis thaliana, Saccharomyces cerevisiae

Plant Physiol.

169

1042-1061

2015

-

1

-

2

-

1

2

-

2

-

4

-

2

-

3

1

-

1

-

3

-

1

3

-

2

-

1

2

-

2

-

2

-

3

1

-

1

-

4

-

1

743862

Karkovska

L-Lactate-selective microbial ...

Ogataea angusta

Talanta

144

1195-1200

2015

-

1

-

1

-

3

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

743847

Smutok

Flavocytochrome b2-based enzy ...

Ogataea angusta, Ogataea angusta tr1

ScientificWorldJournal

2013

461284

2013

-

1

-

1

-

4

-

4

-

1

-

1

-

6

1

-

1

-

4

-

1

-

4

-

1

-

4

-

1

-

1

-

6

1

-

1

-

1

-

722066

Smutok

Chromate-reducing activity of ...

Ogataea angusta, Ogataea angusta C-105

Chemosphere

83

449-454

2011

-

1

-

1

-

4

-

5

-

1

-

1

-

8

-

1

-

1

-

2

-

1

-

2

-

1

-

4

-

1

-

1

-

8

-

1

-

1

-

722153

Lederer

Another look at the interactio ...

Saccharomyces cerevisiae

Eur. Biophys. J.

40

1283-1299

2011

-

1

-

13

2

-

1

-

4

-

1

-

1

-

5

1

-

4

-

4

1

-

13

2

-

1

-

1

-

5

1

-

695890

Mowat

Flavin-containing heme enzymes ...

Saccharomyces cerevisiae

Arch. Biochem. Biophys.

493

37-52

2010

-

4

-

1

-

1

-

1

-

2

-

2

-

4

-

1

-

1

-

1

-

712523

Sakai

Functional replacement of yeas ...

Saccharomyces cerevisiae, Saccharomyces cerevisiae D273-10B/A1

J. Biosci. Bioeng.

110

269-272

2010

-

1

-

1

-

2

-

3

-

2

1

-

2

-

1

2

-

1

-

2

-

2

1

-

712759

Diep Le

Structural evidence for the fu ...

Saccharomyces cerevisiae

J. Mol. Biol.

400

518-530

2010

-

1

-

2

-

1

-

2

-

1

-

2

-

2

1

-

2

-

1

-

1

-

721242

Arzi

-

Flavocytochrome b2 activity in ...

Satureja hortensis

Acta Hortic.

853

369-378

2010

-

1

2

-

1

-

1

-

1

-

2

-

1

-

2

-

2

-

1

2

-

1

-

1

-

2

-

1

-

1

-

696302

Le

Interdomain contacts in flavoc ...

Saccharomyces cerevisiae

Biochemistry

48

10803-10809

2009

-

14

-

15

1

-

1

-

1

-

4

1

-

26

1

-

3

-

3

-

14

-

15

1

-

1

-

4

1

-

26

1

-

1

-

696507

Shkil

Bioelectrochemical detection o ...

Saccharomyces cerevisiae

Bioelectrochemistry

76

175-179

2009

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

697905

Tabacchi

L-lactate dehydrogenation in f ...

Saccharomyces cerevisiae

FEBS J.

276

2368-2380

2009

-

1

-

1

-

3

1

-

1

-

1

-

1

-

3

1

-

700066

Dmitruk

Construction of flavocytochrom ...

Ogataea angusta

Microbiology

77

213-218

2008

-

1

-

1

-

4

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

672749

Hao

Pseudomonas stutzeri as a nove ...

Pseudomonas stutzeri

Biotechnol. Lett.

29

105-110

2007

-

1

-

1

-

1

-

1

-

1

-

685107

Boubacar

Flavocytochrome b2: reactivity ...

Saccharomyces cerevisiae

Biochemistry

46

13080-13088

2007

-

1

-

1

-

1

-

2

-

1

2

-

1

-

1

-

1

-

1

-

1

2

-

685150

Cenas

Potentiometric and further kin ...

Saccharomyces cerevisiae

Biochemistry

46

4661-4670

2007

-

1

-

1

-

6

18

-

3

-

1

-

19

-

1

4

-

1

-

1

-

6

4

18

-

1

-

19

-

685174

Tsai

Mechanistic and structural stu ...

Saccharomyces cerevisiae

Biochemistry

46

7844-7851

2007

-

1

-

4

-

1

-

1

-

1

-

4

1

-

1

-

1

-

4

-

1

-

1

-

4

1

-

685700

Smutok

Permeabilized cells of flavocy ...

Ogataea angusta

Biosens. Bioelectron.

23

599-605

2007

-

1

-

2

-

4

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

675858

Smutok

-

Screening of yeasts producing ...

Ogataea angusta, Ogataea angusta 356, Ogataea angusta K-105, Saccharomyces cerevisiae, Saccharomyces cerevisiae IZR-106, Saccharomyces cerevisiae IZR-42

Microbiology

75

20-24

2006

-

6

-

4

-

4

-

655069

Smutok

A novel L-lactate-selective bi ...

Ogataea angusta

Biosens. Bioelectron.

20

1285-1290

2005

-

1

-

3

-

1

-

654138

Keyhani

-

Expression of L-lactate dehydr ...

Crocus sativus

Acta Hortic.

650

109-117

2004

-

1

-

1

-

2

-

3

-

1

-

2

-

3

-

654766

Mowat

Altered substrate specificity ...

Saccharomyces cerevisiae

Biochemistry

43

9519-9526

2004

-

1

2

-

2

-

1

-

1

2

-

654235

Gaida

-

A new method of visualization ...

Ogataea angusta

Appl. Biochem. Microbiol.

39

221-223

2003

-

1

-

1

-

1

-

654520

Le

Epitope mapping for the monocl ...

Saccharomyces cerevisiae

Biochem. J.

373

115-123

2003

-

14

-

1

-

14

-

654690

Sobrado

Solvent and primary deuterium ...

Saccharomyces cerevisiae

Biochemistry

42

15208-15214

2003

-

1

-

2

-

2

-

1

-

1

-

2

-

1

-

2

-

1

-

2

-

348078

Cunane

Crystallographic study of the ...

Saccharomyces cerevisiae

Biochemistry

41

4264-4272

2002

-

1

2

-

1

-

1

-

1

-

4

1

-

3

-

1

3

1

2

-

1

-

1

-

4

1

-

656765

Keyhani

Catalytic properties of three ...

Crocus sativus

Mol. Biol. Rep.

29

163-166

2002

-

2

3

-

1

-

1

-

3

-

2

-

3

-

1

-

3

-

348077

Gondry

The catalytic role of tyrosine ...

Saccharomyces cerevisiae

Eur. J. Biochem.

268

4918-4927

2001

-

1

-

2

-

5

-

2

1

-

1

-

2

-

1

-

4

-

1

-

1

-

2

-

5

-

2

1

-

1

-

1

-

4

-

348076

Mowat

Kinetic and crystallographic s ...

Saccharomyces cerevisiae

Biochemistry

39

3266-3275

2000

-

1

-

5

11

1

-

3

-

1

-

3

8

1

-

3

-

4

6

-

1

4

1

-

5

6

11

1

-

1

-

3

8

1

-

3

-

348075

Sinclair

Re-design of Saccharomyces cer ...

Saccharomyces cerevisiae

Biochem. J.

333

117-120

1998

-

1

-

5

-

2

-

1

-

1

-

2

-

2

5

-

5

-

1

-

1

-

5

-

2

-

1

-

1

-

2

5

-

5

-

348073

Sharp

Deletions in the interdomain h ...

Saccharomyces cerevisiae

Biochemistry

35

891-899

1996

-

1

-

1

-

1

-

1

-

1

-

4

1

-

1

-

2

-

1

2

-

1

-

1

-

1

-

4

1

-

1

-

348074

Daff

New insights into the catalyti ...

Saccharomyces cerevisiae

Biochemistry

35

6345-6350

1996

-

1

-

1

-

2

1

-

1

-

2

-

1

-

1

3

1

-

1

-

1

-

1

-

2

1

-

1

-

1

-

1

3

1

-

696188

Daff

Interaction of cytochrome c wi ...

Saccharomyces cerevisiae

Biochemistry

35

6351-6357

1996

-

2

-

2

-

2

-

1

-

1

-

3

-

2

-

2

3

-

1

-

1

-

348071

Gaume

Mutation to glutamine of histi ...

Saccharomyces cerevisiae

Biochimie

77

621-630

1995

-

1

3

-

2

4

-

1

-

1

-

1

-

1

-

2

4

-

2

-

1

2

-

1

3

-

2

4

-

1

-

1

-

1

-

2

4

-

2

-

348072

Tegoni

X-ray structure of two complex ...

Saccharomyces cerevisiae

Biochemistry

34

9840-9850

1995

-

1

-

1

-

4

2

1

-

1

-

2

-

1

-

1

4

-

3

-

3

-

1

3

-

1

-

4

2

1

-

1

-

1

-

1

4

-

3

-

696075

Balme

Isolation and characterization ...

Saccharomyces cerevisiae

Biochem. J.

309

601-605

1995

-

1

-

3

-

1

-

2

-

1

-

1

-

3

-

2

-

1

2

-

3

-

1

-

1

-

1

-

3

-

348069

Balme

On the rate of proton exchange ...

Saccharomyces cerevisiae

Protein Sci.

3

109-117

1994

-

1

-

2

-

4

-

1

-

1

-

1

-

1

4

-

3

-

1

-

1

-

2

-

4

-

1

-

1

-

1

4

-

3

-

348070

Daff

-

Strategic manipulation of the ...

Saccharomyces cerevisiae

Biochem. J.

301

829-834

1994

-

1

-

3

-

4

-

1

-

1

-

1

-

1

9

-

5

-

1

-

1

-

3

-

4

-

1

-

1

-

1

9

-

5

-

348068

Silvestrini

Expression in Escherichia coli ...

Wickerhamomyces anomalus

Biochem. J.

295

501-508

1993

-

1

-

1

-

1

-

1

-

3

-

1

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

3

-

348067

Brunt

Isolation and characterization ...

Saccharomyces cerevisiae

Biochem. J.

283

87-90

1992

-

1

-

1

-

3

-

1

-

3

-

1

-

1

-

1

-

1

-

3

-

1

-

348065

Lederer

-

On some aspects of the catalys ...

Saccharomyces cerevisiae

Flavins and Flavoproteins (Proc. Int. Symp. , 10th, Meeting Date 1990, Curti, B. , Ronchi S. , Zanetti, G. , eds. ) de Gruyter, Berlin, New York

773-782

1991

-

1

2

-

4

-

1

-

1

-

1

-

4

-

4

-

3

-

1

3

1

2

-

4

-

1

-

1

-

4

-

4

-

348064

Genet

The carbanion of nitroethane i ...

Saccharomyces cerevisiae

Biochem. J.

266

301-304

1990

-

3

1

-

1

-

1

-

1

-

3

-

1

2

-

1

-

3

2

1

-

1

-

1

-

3

-

348066

Tegoni

Inhibition of L-lactate: cytoc ...

Saccharomyces cerevisiae, Wickerhamomyces anomalus

Eur. J. Biochem.

190

329-342

1990

-

2

4

-

2

-

2

-

2

-

7

-

2

1

-

2

-

2

1

4

-

2

-

2

-

7

-

699506

Xia

Molecular structure of flavocy ...

Saccharomyces cerevisiae

J. Mol. Biol.

212

837-863

1990

-

1

-

1

-

1

-

2

-

2

1

-

1

-

348063

Black

Structural basis for the kinet ...

Saccharomyces cerevisiae, Wickerhamomyces anomalus

Biochem. J.

263

973-976

1989

-

2

-

2

1

2

-

5

-

5

-

2

-

2

-

2

1

2

-

5

-

348062

Ghrir

Primary structure of flavocyto ...

Saccharomyces cerevisiae

Eur. J. Biochem.

139

59-74

1984

-

1

-

1

-

3

-

1

-

3

-

1

-

1

-

1

-

1

-

1

-

3

-

348060

Blazy

A standard high-yield purifica ...

Wickerhamomyces anomalus

Anal. Biochem.

88

624-633

1978

-

1

-

1

-

1

-

1

-

1

2

1

-

1

-

1

-

1

-

1

-

1

-

1

2

1

-

348061

Labeyrie

Flavocytochrome b 2 or L-lacta ...

Saccharomyces cerevisiae, Wickerhamomyces anomalus

Methods Enzymol.

53

238-256

1978

-

1

-

1

6

4

-

2

5

2

-

3

-

2

-

2

5

2

-

1

-

6

7

-

6

1

-

1

-

6

7

4

-

2

5

2

-

2

-

2

5

2

-

1

-

287801

Hatefi

-

Metal-containing flavoprotein ...

Saccharomyces cerevisiae, Wickerhamomyces anomalus

The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )

13

175-297

1976

-

2

-

2

3

2

-

2

-

6

2

-

8

-

8

-

2

-

2

3

2

-

6

2

-

348058

Jacq

Cytochrome b2 from bakers yeas ...

Saccharomyces cerevisiae

Eur. J. Biochem.

41

311-320

1974

-

1

2

1

-

2

-

1

-

1

3

1

-

3

-

3

-

1

2

1

-

1

-

1

3

1

-

348057

Guiard

Yeast L-lactate dehydrogenase ...

Saccharomyces cerevisiae

Eur. J. Biochem.

34

241-247

1973

-

1

-

1

-

1

-

3

1

-

2

-

2

-

1

-

1

-

3

1

-

348056

Pritchard

An NAD+-independent L-lactate ...

Rhizopus oryzae

Biochim. Biophys. Acta

250

25-34

1971

-

1

-

1

-

1

-

1

-

1

-

3

-

4

-

1

-

2

-

2

-

1

2

1

-

1

-

1

-

1

-

3

-

4

-

1

-

The catalytic role of tyrosine 254 in flavocytochrome b2 (L-lactate dehydrogenase from baker's yeast). Comparison between the Y254F and Y254L mutant proteins

Data extracted from this reference: