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Literature summary for 1.1.1.B40 extracted from

  • Jang, C.; Obeyesekere, V.R.; Dilley, R.J.; Alford, F.P.; Inder, W.J.
    11beta Hydroxysteroid dehydrogenase type 1 is expressed and is biologically active in human skeletal muscle (2006), Clin. Endocrinol. (Oxf.), 65, 800-805.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cortisol + NAD+ Homo sapiens isozyme 11beta-HSD2 catalyzes the reverse reaction 11beta-HSD1 with cofactor NAD+ cortisone + NADH
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ir

Organism

Organism UniProt Comment Textmining
Homo sapiens
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female and male, isozymes 11beta-HSD1 and 11beta-HSD2
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cortisol + NAD+ isozyme 11beta-HSD2 catalyzes the reverse reaction 11beta-HSD1 with cofactor NAD+ Homo sapiens cortisone + NADH
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ir

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens