Application | Comment | Organism |
---|---|---|
synthesis | synthesis of (R)-1,3-butanediol from its racemate by stereoselective oxidation of the (S)-isomer using (S)-specific secondary alcohol dehydrogenase in whole recombinant Escherichia coli cells. Yield of the (R)-product reaches 72.6 g/l, with a molar recovery yield of 48.4% and an optical purity of 95% enantiomeric excess | Candida parapsilosis |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Candida parapsilosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida parapsilosis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-1,3-butanediol + NAD+ + H+ | - |
Candida parapsilosis | 4-hydroxy-2-butanone + NADH | enantioselective oxidation of the (S)-isomer | ? |
Synonyms | Comment | Organism |
---|---|---|
SADH | - |
Candida parapsilosis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Candida parapsilosis | |
NADH | - |
Candida parapsilosis |