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Literature summary for 1.1.1.B19 extracted from
- Xylose enhances furfural tolerance in Candida tropicalis by improving NADH recycle (2017), Chem. Eng. Sci., 158, 37-40 .
No PubMed abstract available
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Candida tropicalis | Candida tropicalis can use xylose in hemicellulose hydrolysate | ? | - |
- |
 |
| xylitol + NAD+ | Candida tropicalis | - |
L-xylulose + NADH + H+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida tropicalis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Candida tropicalis can use xylose in hemicellulose hydrolysate | Candida tropicalis | ? | - |
- |
|
| additional information | xylitol dehydrogenase almost exclusively uses NAD+ as cofactor in the dehydrogenation of xylitol into xylulose | Candida tropicalis | ? | - |
- |
|
| xylitol + NAD+ | - |
Candida tropicalis | L-xylulose + NADH + H+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| xylitol dehydrogenase | - |
Candida tropicalis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | xylitol dehydrogenase almost exclusively uses NAD+ as cofactor in the dehydrogenation of xylitol into xylulose | Candida tropicalis | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | furfural is one of the typical inhibitors present in hemicellulose hydrolysate. Furfural is harmful to cell growth and biofuel production in microbes. Candida tropicalis obtains better furfural tolerance in xylose medium. The dehydrogenation of xylitol, which produces coenzyme NADH, promotes the recycle of NAD+ and facilitates the reduction of furfural. The rate of furfural degradation and half maximal inhibitory concentration for furfural of Candida tropicalis in xylose medium increases 1.68fold and 1.19fold, respectively | Candida tropicalis |
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Release 2023.1 (January 2023)
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