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Literature summary for 1.1.1.95 extracted from
- Molecular cloning and expression of phosphoglycerate dehydrogenase and phosphoserine aminotransferase in the serine biosynthetic pathway from Acanthamoeba castellanii (2015), Parasitol. Res., 114, 1387-1395.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) cells | Acanthamoeba castellanii |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 47700 | - |
- |
Acanthamoeba castellanii |
| 50000 | - |
x * 50000, SDS-PAGE | Acanthamoeba castellanii |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-phospho-D-glycerate + NAD+ | Acanthamoeba castellanii | - |
3-phosphonooxypyruvate + NADH + H+ | - |
? |  |
| 3-phospho-D-glycerate + NAD+ | Acanthamoeba castellanii ATCC 30011 | - |
3-phosphonooxypyruvate + NADH + H+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acanthamoeba castellanii | U3RH61 | - |
- |
| Acanthamoeba castellanii ATCC 30011 | U3RH61 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Acanthamoeba castellanii |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| trophozoite | - |
Acanthamoeba castellanii | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-phospho-D-glycerate + NAD+ | - |
Acanthamoeba castellanii | 3-phosphonooxypyruvate + NADH + H+ | - |
? | |
| 3-phospho-D-glycerate + NAD+ | - |
Acanthamoeba castellanii ATCC 30011 | 3-phosphonooxypyruvate + NADH + H+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 50000, SDS-PAGE | Acanthamoeba castellanii |
| ? | x * 47700, calculated from amino acid sequence | Acanthamoeba castellanii |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGDH | - |
Acanthamoeba castellanii |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Acanthamoeba castellanii | |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Acanthamoeba castellanii | calculated from amino acid sequence | - |
7.6 |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Acanthamoeba castellanii | there is no significant change in the mRNA expression level after the incubation with L-serine | additional information |
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