Literature summary for 1.1.1.76 extracted from

Dias, B.D.C.; Lima, M.E.D.N.V.; Vollu, R.E.; da Mota, F.F.; da Silva, A.J.R.; de Castro, A.M.; Freire, D.M.G.; Seldin, L.
2,3-Butanediol production by the non-pathogenic bacterium Paenibacillus brasilensis (2018), Appl. Microbiol. Biotechnol., 102, 8773-8782 .

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Organism

Organism	UniProt	Comment	Textmining
Paenibacillus brasilensis	-	-	-
Paenibacillus brasilensis PB24	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	although the gene encoding (S,S)-2,3-butanediol dehydrogenase is found in the genome of Paenibacillus brasilensis strain PB24, only R,R-2,3-butanediol ((R,R)-2,3-butanediol dehydrogenase, EC 1.1.1.4) and meso-2,3-butanediol are detected by gas chromatography under the growth conditions (modified YEPD medium, pH 6.3, 32°C, up to 72 h)	Paenibacillus brasilensis	?	-	-
additional information	although the gene encoding (S,S)-2,3-butanediol dehydrogenase is found in the genome of Paenibacillus brasilensis strain PB24, only R,R-2,3-butanediol ((R,R)-2,3-butanediol dehydrogenase, EC 1.1.1.4) and meso-2,3-butanediol are detected by gas chromatography under the growth conditions (modified YEPD medium, pH 6.3, 32°C, up to 72 h)	Paenibacillus brasilensis PB24	?	-	-

Synonyms

Synonyms	Comment	Organism
ButA	-	Paenibacillus brasilensis
S-2,3-butanediol dehydrogenase	-	Paenibacillus brasilensis

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Paenibacillus brasilensis
NADH	-	Paenibacillus brasilensis

General Information

General Information	Comment	Organism
metabolism	the proposed pathway from glucose to 2,3-butanediol in Paenibacillus brasilensis involves the enzyme, overview	Paenibacillus brasilensis
physiological function	besides encoding diacetyl reductase, the butA gene is also responsible for the expression of S-2,3-butanediol dehydrogenase, which may direct the pathway for production of S,S-2,3-BDO and meso-2,3-BDO	Paenibacillus brasilensis

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Release 2023.1 (January 2023)