Literature summary for 1.1.1.67 extracted from

Zhang, M.; Gu, L.; Cheng, C.; Zhu, J.; Wu, H.; Ma, J.; Dong, W.; Kong, X.; Jiang, M.; Ouyang, P.
High-yield production of mannitol by Leuconostoc pseudomesenteroides CTCC G123 from chicory-derived inulin hydrolysate (2017), J. Ind. Microbiol. Biotechnol., 44, 1237-1244 .

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Application

Application	Comment	Organism
synthesis	an effective strategy for producing high yields of mannitol is developed. The combined strategies of aeration induction and redox modulation significantly increases the glucose consumption rate, intracellular NADH level and the specific activity of mannitol dehydrogenase (MDH), resulting in an increase in mannitol production from 64.6 to 88.1 g/l with the yield increased from 0.69 to 0.94 g/g	Leuconostoc pseudomesenteroides

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-fructose + NADH + H+	Leuconostoc pseudomesenteroides	-	D-mannitol + NAD+	-	?
D-fructose + NADH + H+	Leuconostoc pseudomesenteroides CTCC G123	-	D-mannitol + NAD+	-	?

Organism

Organism	UniProt	Comment	Textmining
Leuconostoc pseudomesenteroides	-	-	-
Leuconostoc pseudomesenteroides CTCC G123	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-fructose + NADH + H+	-	Leuconostoc pseudomesenteroides	D-mannitol + NAD+	-	?
D-fructose + NADH + H+	-	Leuconostoc pseudomesenteroides CTCC G123	D-mannitol + NAD+	-	?

Synonyms

Synonyms	Comment	Organism
mannitol dehydrogenase	-	Leuconostoc pseudomesenteroides
MDH	-	Leuconostoc pseudomesenteroides

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Release 2023.1 (January 2023)