Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | 17beta-HSD1 and 17beta-HSD2 inhibitor structures and their biological activities are reviewed; 17beta-HSD1 and 17beta-HSD2 inhibitor structures and their biological activities are reviewed. Dual 17beta-HSD1/STS inhibitors and inhibitors are covered | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrogenic estrone + NAD(P)H + H+ | Homo sapiens | the product 17beta-estradiol plays a central role in the etiology of estrogen dependent diseases | 17beta-estradiol + NAD(P)+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14061 | - |
- |
Homo sapiens | P37059 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17beta-estradiol + NAD(P)+ | - |
Homo sapiens | estrone + NAD(P)H + H+ | - |
? | |
estrogenic estrone + NAD(P)H + H+ | the product 17beta-estradiol plays a central role in the etiology of estrogen dependent diseases | Homo sapiens | 17beta-estradiol + NAD(P)+ | - |
? | |
estrone + NAD(P)H + H+ | - |
Homo sapiens | 17beta-estradiol + NAD(P)+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD1 | - |
Homo sapiens |
17beta-HSD2 | - |
Homo sapiens |
17beta-hydroxysteroid dehydrogenase type 1 | - |
Homo sapiens |
17beta-hydroxysteroid dehydrogenase type 2 | - |
Homo sapiens |