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Literature summary for 1.1.1.62 extracted from

  • Song, D.; Liu, G.; Luu-The, V.; Zhao, D.; Wang, L.; Zhang, H.; Xueling, G.; Li, S.; Desy, L.; Labrie, F.; Pelletier, G.
    Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study (2006), J. Steroid Biochem. Mol. Biol., 101, 136-144.
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
breast carcinoma cell 17beta-HSD type 12 in 83% of the breast cancer specimen. The expression of 17beta-HSD type 12 is significantly higher in breast carcinoma specimen than in normal tissues Homo sapiens
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breast carcinoma cell 17beta-HSD type 7 activity is detected in 47% of the breast cancer specimen Homo sapiens
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breast carcinoma cell the 17beta-HSD type 1 can be detected only in one tumor Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estrone + NAD(P)H + H+
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 Homo sapiens estradiol-17beta + NAD(P)+
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 ?

Synonyms

Synonyms Comment Organism
17beta-HSD type 1
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 Homo sapiens
17beta-HSD type 12
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 Homo sapiens
17beta-HSD type 7
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 Homo sapiens
17beta-hydroxysteroid dehydrogenase type 1
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 Homo sapiens
17beta-hydroxysteroid dehydrogenase type 12
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 Homo sapiens
17beta-hydroxysteroid dehydrogenase type 7
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 Homo sapiens