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Literature summary for 1.1.1.47 extracted from
- Hexose-6-phosphate dehydrogenase in the endoplasmic reticulum (2010), Biol. Chem., 391, 1-8.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0015 | - |
D-glucose 6-phosphate | pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus |  |
| 0.026 | - |
NADP+ | pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
| 0.049 | - |
D-glucose 6-phosphate | pH not specified in the publication, temperature not specified in the publication | Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum lumen | - |
Mus musculus | 5788 | - |
| endoplasmic reticulum lumen | - |
Homo sapiens | 5788 | - |
| endoplasmic reticulum lumen | - |
Rattus norvegicus | 5788 | - |
| endoplasmic reticulum lumen | - |
Oryctolagus cuniculus | 5788 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 89000 | - |
2 * 89000, 791 amino acid residues | Homo sapiens |
| 90000 | - |
2 * 90000, deduced from genome sequence | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | modified residues: 157, 282, 683 | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adipose tissue | - |
Rattus norvegicus | - |
| adipose-derived stem cell | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
| neutrophil | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glucose 6-phosphate + NADP+ | - |
Mus musculus | D-glucono-1,5-lactone 6-phosphate + NADPH + H+ | - |
? | |
| D-glucose 6-phosphate + NADP+ | - |
Rattus norvegicus | D-glucono-1,5-lactone 6-phosphate + NADPH + H+ | - |
? | |
| D-glucose 6-phosphate + NADP+ | - |
Oryctolagus cuniculus | D-glucono-1,5-lactone 6-phosphate + NADPH + H+ | - |
? | |
| D-glucose 6-phosphate + NADP+ | other substrates: hexose-6-phosphates, glucose-6-sulfate, glucose | Homo sapiens | D-glucono-1,5-lactone 6-phosphate + NADPH + H+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | - |
Mus musculus |
| homodimer | - |
Oryctolagus cuniculus |
| homodimer | 2 * 89000, 791 amino acid residues | Homo sapiens |
| homodimer | 2 * 90000, deduced from genome sequence | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| hexose-6-phosphate dehydrogenase | - |
Mus musculus |
| hexose-6-phosphate dehydrogenase | - |
Homo sapiens |
| hexose-6-phosphate dehydrogenase | - |
Rattus norvegicus |
| hexose-6-phosphate dehydrogenase | - |
Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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