Literature summary for 1.1.1.44 extracted from

Ganea, E.; Harding, J.J.
Inhibition of 6-phosphogluconate dehydrogenase by carbamylation and protection by alpha-crystallin, a chaperone-like protein (1996), Biochem. Biophys. Res. Commun., 222, 626-631.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6-phospho-D-gluconate + NADP+	Homo sapiens	enzyme specific for the oxidative pentose phosphate pathway	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	human	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-
lens	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6-phospho-D-gluconate + NADP+	-	Homo sapiens	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r
6-phospho-D-gluconate + NADP+	enzyme specific for the oxidative pentose phosphate pathway	Homo sapiens	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r

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Release 2023.1 (January 2023)