Literature summary for 1.1.1.44 extracted from

Abdallah, M.A.; Adams, M.J.; Archibald, I.G.; Bielmann, J.F.; Helliwell, J.R.; Jenkins, S.E.
Binding of coenzyme and substrate and coenzyme analogues to 6-phosphogluconate dehydrogenase from sheep liver (1979), Eur. J. Biochem., 98, 121-130.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Ovis aries

Inhibitors

Inhibitors	Comment	Organism	Structure
phosphate	-	Ovis aries

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
50000	-	2 * 50000	Ovis aries

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6-phospho-D-gluconate + NADP+	Ovis aries	enzyme specific for the oxidative pentose phosphate pathway	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r

Organism

Organism	UniProt	Comment	Textmining
Ovis aries	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Ovis aries

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Ovis aries	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6-phospho-D-gluconate + NADP+	-	Ovis aries	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r
6-phospho-D-gluconate + NADP+	enzyme specific for the oxidative pentose phosphate pathway	Ovis aries	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r

Subunits

Subunits	Comment	Organism
dimer	2 * 50000	Ovis aries

Cofactor

Cofactor	Comment	Organism	Structure
NADP+	-	Ovis aries

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Release 2023.1 (January 2023)