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Literature summary for 1.1.1.42 extracted from

  • Tames-Espinosa, M.; Martinez, I.; Romero-Kutzner, V.; Bondyale-Juez, D.; Packard, T.; Gomez, M.
    NADP+-dependent isocitrate dehydrogenase activity in marine plankton (2018), Mar. Chem., 204, 86-94 .
No PubMed abstract available
Search for more literature for 1.1.1.42

General Stability

General Stability Organism
the enzyme activity drops continuously per time during 500 min measurements with an average lost of 1.1% of enzyme activity per 10 min marine plankton environmental sample

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.022
-
 NADP+ at pH 8.2 and 18°C marine plankton environmental sample
0.232
-
 isocitrate at pH 8.2 and 18°C marine plankton environmental sample

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ 6 mM used in assay conditions marine plankton environmental sample

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NADP+ marine plankton environmental sample
-
 2-oxoglutarate + CO2 + NADPH + H+
-
 r

Organism

Organism UniProt Comment Textmining
marine plankton environmental sample
-
 zooplankton and microplankton
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate + NADP+
-
 marine plankton environmental sample 2-oxoglutarate + CO2 + NADPH + H+
-
 r

Synonyms

Synonyms Comment Organism
NADP+-dependent isocitrate dehydrogenase
-
 marine plankton environmental sample
NADP-IDH
-
 marine plankton environmental sample

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
28
-
-
 marine plankton environmental sample

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.2
-
-
 marine plankton environmental sample

pH Range

pH Minimum pH Maximum Comment Organism
7.6 8.8 measurements below pH 7.6 and above pH 8.8 lead to activities lower than 50% of its Vmax value marine plankton environmental sample

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 marine plankton environmental sample