BRENDA - Enzyme Database
show all sequences of 1.1.1.407

ATP-binding cassette (ABC) transport system solute-binding protein-guided identification of novel D-altritol and galactitol catabolic pathways in Agrobacterium tumefaciens C58

Wichelecki, D.; Vetting, M.; Chou, L.; Al-Obaidi, N.; Bouvier, J.; Almo, S.; Gerlt, J.; J. Biol. Chem. 290, 28963-28976 (2015)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.4
-
D-altritol
pH 9.0, 25°C
Agrobacterium fabrum
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Zn2+
enzyme is a zinc-binding dehydrogenase, member of Pfam Family PF00107
Agrobacterium fabrum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
D-altritol + NAD+
Agrobacterium fabrum
-
D-tagatose + NADH + H+
-
-
?
D-altritol + NAD+
Agrobacterium fabrum C58
-
D-tagatose + NADH + H+
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Agrobacterium fabrum
A9CES3
-
-
Agrobacterium fabrum C58
A9CES3
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
D-altritol + NAD+
-
740741
Agrobacterium fabrum
D-tagatose + NADH + H+
-
-
-
?
D-altritol + NAD+
-
740741
Agrobacterium fabrum C58
D-tagatose + NADH + H+
-
-
-
?
D-arabitol + NAD+
-
740741
Agrobacterium fabrum
? + NADH + H+
-
-
-
?
D-arabitol + NAD+
-
740741
Agrobacterium fabrum C58
? + NADH + H+
-
-
-
?
D-mannitol + NAD+
-
740741
Agrobacterium fabrum
? + NADH + H+
-
-
-
?
D-mannitol + NAD+
-
740741
Agrobacterium fabrum C58
? + NADH + H+
-
-
-
?
additional information
D-altritol is oxidized at a significantly greater rate than D-mannitol and D-arabitol
740741
Agrobacterium fabrum
?
-
-
-
-
additional information
D-altritol is oxidized at a significantly greater rate than D-mannitol and D-arabitol
740741
Agrobacterium fabrum C58
?
-
-
-
-
Synonyms
Synonyms
Commentary
Organism
Atu3163
-
Agrobacterium fabrum
Turnover Number [1/s]
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.9
-
D-altritol
pH 9.0, 25°C
Agrobacterium fabrum
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.4
-
D-altritol
pH 9.0, 25°C
Agrobacterium fabrum
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Zn2+
enzyme is a zinc-binding dehydrogenase, member of Pfam Family PF00107
Agrobacterium fabrum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
D-altritol + NAD+
Agrobacterium fabrum
-
D-tagatose + NADH + H+
-
-
?
D-altritol + NAD+
Agrobacterium fabrum C58
-
D-tagatose + NADH + H+
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
D-altritol + NAD+
-
740741
Agrobacterium fabrum
D-tagatose + NADH + H+
-
-
-
?
D-altritol + NAD+
-
740741
Agrobacterium fabrum C58
D-tagatose + NADH + H+
-
-
-
?
D-arabitol + NAD+
-
740741
Agrobacterium fabrum
? + NADH + H+
-
-
-
?
D-arabitol + NAD+
-
740741
Agrobacterium fabrum C58
? + NADH + H+
-
-
-
?
D-mannitol + NAD+
-
740741
Agrobacterium fabrum
? + NADH + H+
-
-
-
?
D-mannitol + NAD+
-
740741
Agrobacterium fabrum C58
? + NADH + H+
-
-
-
?
additional information
D-altritol is oxidized at a significantly greater rate than D-mannitol and D-arabitol
740741
Agrobacterium fabrum
?
-
-
-
-
additional information
D-altritol is oxidized at a significantly greater rate than D-mannitol and D-arabitol
740741
Agrobacterium fabrum C58
?
-
-
-
-
Turnover Number [1/s] (protein specific)
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.9
-
D-altritol
pH 9.0, 25°C
Agrobacterium fabrum
KCat/KM [mM/s]
kcat/KM Value [1/mMs-1]
kcat/KM Value Maximum [1/mMs-1]
Substrate
Commentary
Organism
Structure
1.4
-
D-altritol
pH 9.0, 25°C
Agrobacterium fabrum
KCat/KM [mM/s] (protein specific)
KCat/KM Value [1/mMs-1]
KCat/KM Value Maximum [1/mMs-1]
Substrate
Commentary
Organism
Structure
1.4
-
D-altritol
pH 9.0, 25°C
Agrobacterium fabrum
Other publictions for EC 1.1.1.407
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
740741
Wichelecki
ATP-binding cassette (ABC) tra ...
Agrobacterium fabrum, Agrobacterium fabrum C58
J. Biol. Chem.
290
28963-28976
2015
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