Literature summary for 1.1.1.406 extracted from

Liu, J.J.; Zhang, G.C.; Kwak, S.; Oh, E.J.; Yun, E.J.; Chomvong, K.; Cate, J.H.D.; Jin, Y.S.
Overcoming the thermodynamic equilibrium of an isomerization reaction through oxidoreductive reactions for biotransformation (2019), Nat. Commun., 10, 1356 .

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Application

Application	Comment	Organism
synthesis	the two oxidoreductases, xylose reductase and galactitol dehydrogenase are functionally expressed in the engineered yeast (EJ2g_pXpG) and enable direct production of tagatose from lactose. The expression levels of the enzymes are adjusted to maximize tagatose production. The resulting engineered yeast produces 37.69 g/L of tagatose from lactose with a tagatose and galactose ratio of 9:1 in the reaction broth	Rhizobium leguminosarum

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in the engineered yeast (EJ2g_pXpG)	Rhizobium leguminosarum

Organism

Organism	UniProt	Comment	Textmining
Rhizobium leguminosarum	-	-	-

Synonyms

Synonyms	Comment	Organism
galactitol dehydrogenase	-	Rhizobium leguminosarum

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Release 2023.1 (January 2023)